BACKGROUND Central venous catheters in patients with cancer are associated with development of deep vein thrombosis (DVT); however, there is no accepted standard treatment. OBJECTIVES To assess the safety and effectiveness of a management strategy for central venous catheter-related DVT in cancer patients consisting of dalteparin and warfarin without the need for line removal. PATIENTS/METH...

OBJECTIVES To develop a computerized Digit Vigilance Test (C-DVT) with lower random measurement error than that of the DVT and to examine the concurrent validity, ecological validity, and test-retest reliability of the C-DVT in patients with stroke. DESIGN A cross-sectional study. PATIENTS Forty-four patients with stroke. METHODS We developed and tested the C-DVT. To examine the psychomet...

An underappreciated sequelae of deep venous thrombosis (DVT) is the pain associated with the blood clot in the peripheral extremity. Although most frequently acute in nature, DVT occasionally presents with chronic pain in the affected limb. Furthermore, many individuals suffering from prothrombotic states often have recurring pain from DVT. Thus far there has been a paucity in the medical liter...

BACKGROUND Anticoagulation is recommended as standard of care for venous thromboembolism (VTE) (pulmonary embolism [PE]/deep vein thrombosis [DVT]), for which unfractionated heparin (UFH) and warfarin are used in Japan. In the multi-regional AMPLIFY study, a fixed-dose regimen of apixaban alone was non-inferior to conventional therapy for treatment of PE/DVT and was associated with significantl...

May-Thurner syndrome (MTS) has been recognized as a clinical entity for almost six decades. The true incidence rate of MTS is unknown and perhaps ranges from 22 to 32% according to the autopsy studies in the early twentieth century. However, MTS related deep venous thrombosis (DVT) accounts for only 2%-3% of all lower limb DVTS. In MTS, the left common iliac vein is compressed against the fifth...

BACKGROUND Diabetic myonecrosis is an uncommon complication of long-standing poorly controlled diabetes mellitus. It presents as acute non-traumatic swelling and pain of the lower extremity, which can mimic deep vein thrombosis (DVT). The clinical course is usually self-limiting and patients respond well to supportive medical therapy. CASE REPORT A 54-year-old male with past medical history of ...

M e t h o d s Design: 2 randomized, controlled, noninferiority trials. Allocation: Concealed.* Blinding: Blinded (central outcome adjudication committee).* Follow-up period: 3 and 6 months. Setting: 318 centers in 25 countries in North and South America, Europe, Africa, and Australia/New Zealand. Patients: Patients ≥ 18 years of age with acute symptomatic DVT (n = 2904, mean age 58 y, 54% men) ...

Thrombosis or thromboembolism (VTE) is a potentially fatal problem encountered in hospitalized patients. Manifesting as deep vein thrombosis (DVT) and pulmonary embolism (PE), the condition often remains unrecognized due to its “silent” character and delayed emergence. The full extent of the problem is also not known because – even in developed countries – underreporting occurs, most often also...

BACKGROUND To investigate the usefulness of popliteal artery spectral doppler findings as a complimentary approach to isolated calf vein thrombosis (DVT). MATERIAL/METHODS We included consecutive patients presenting with symptomatic and sonographically proven acute isolated calf DVT. Patients with thrombosis of any other vein were excluded. We classified calf vein into into four main types. W...