A 6-year-old previously healthy female from the United States presented with 5 days of high fever to 103F, abdominal pain, and vomiting. Exposure history included recent travel Russia, Turkey, Yosemite, San Diego Zoo, as well multiple mosquito bites. On admission, she was found have thrombocytopenia, hematuria, nephrotic range proteinuria subsequently developed acute kidney injury. Her grandfat...

background: iga nephropathy, a prevalent disease in asia, is considered the main cause of end stage renal disease among primary glomerular disease. objective: to determine the frequency of different clinical, histopathological and immunofluorescent characteristics of iga nephropathy. methods: renal biopsies of 376 patients were received for immunofluorescent and for histopathological studies. b...

Introduction: The contribution of renal biopsy is major importance in many paediatrics diseases. This prospective study analysed the clinic-pathological spectrum biopsied cases, complications related to and its effect on management. Methods: USG guided percutaneous was performed indicated children. Laboratory findings, procedure, histological diagnosis management were obtained from all patients...

Objective : to study the effect of total expression vascular endothelial growth factor A (VEGF A), tissue β1 (TGF-β1) and monocytic chemoattractant 1 (MCP-1) on course glomerulonephritis. Material methods was a prospective (12-month) open comparative clinical morphological with inclusion 75 patients aged 18 years (males - 52, females 23) glomerulonephritis in acute stage. All were initially exa...

SUMMARY Hemodynamic functions and blood volume were observed in patients with chronic uremia. Thirty-one patients had clinical features of circulatory congestion and 37 did not. The degree of anemia and acidosis was comparable in both groups. However, cre-atinine clearance was significantly lower in patients with circulatory congestion. Both groups of patients had greater blood pressure, heart ...

Proliferative glomerulonephritis (GN) with monoclonal immunoglobulin deposits (PGNMIDs) is a recently described entity among the spectrum of gammopathy renal significance (MGRS). The disease limited and manifests in chronic glomerular disease, altered function albuminuria, sometimes nephrotic range. Acute nephritic syndrome rare. Until recently, absence criteria for symptomatic haematological p...

BACKGROUND Children and adolescents with end-stage renal disease (ESRD) in sub-Saharan Africa may have the worst outcomes globally. Barriers to management include late presentation, poor socioeconomic conditions, absence of medical insurance, limited diagnostic facilities and non-availability of chronic renal replacement therapy (RRT). Our study was to determine the incidence, aetiology, manage...

BACKGROUND Lymphoproliferative disorders causing paraproteinemia can be associated with various kidney injuries including the deposition of monoclonal immunoglobulins (Ig). A known glomerular manifestation of Waldenström's macroglobulinemia is characterized by prominent intracapillary hyaline thrombi and lack of conspicuous glomerular proliferation. The present case was special in 2 aspects: 1....

INTRODUCTION Kidney involvement in non-Hodgkin lymphoma is recognized but mostly diagnosed following a diagnosis of lymphoma. We describe a rare case of mantle cell lymphoma, a B-cell-type non-Hodgkin lymphoma, first presenting with immune complex glomerulonephritis. CASE PRESENTATION We report the case of a 58-year-old Sri Lankan man who presented with gross hematuria. Further investigation ...

Normal kidney aging is related to tissue and functional changes that make older patients very vulnerable to environmental modifications. Numerous factors can accelerate the impairment of renal function during aging. It was a single-center retrospective study extending over a period of 30 years from 1984 to 2014 and includes patients older than 65 years, hospitalized for nephropathy requiring re...