BACKGROUND Explanation of the ultimate causes of acute and chronic pancreatitis is challenging. Hence, it is necessary to seek various etiological factors, including genetic mutations that may be of importance in triggering recurrence and progression of acute to chronic pancreatitis. The aim of this study was to determine the frequency of genetic mutations in patients with acute pancreatitis an...

Recently, the original Atlanta classification of 1992 was revised and updated by the Working Group using a web-based consultative process involving multiple international pancreatic societies. The new understanding of the disease, its natural history, and objective description and classification of pancreatic and peripancreatic fluid collections make this new 2012 classification a potentially v...

Severe hypertriglyceridemia accounts for up to 7% of all cases of acute pancreatitis. Heparin and insulin activate lipoprotein lipase (LPL), thereby reducing plasma triglyceride levels. However, the safety and efficacy of heparin and insulin in the treatment of hypertriglyceridemia-associated acute pancreatitis have not been well established yet. We successfully used heparin and insulin as firs...

BACKGROUND: Acute pancreatitis rarely complicates pregnancy. Although most pregnant women with acute pancreatitis have associated gallstones, less common causes such as drugs have been reported. CASE PRESENTATION: We report the case of a 34-year-old woman who underwent medical abortion with mifepristone and gemeprost and received codeine as pain-relief during the induction of abortion. She deve...

Introduction: Acute Pancreatitis is a common disease in our region. It can range from mild to severe with high mortality rate. critical identify patients who are at risk for course, since they require close monitoring and immediate aggressive treatment.
 Aims: To compare the effectiveness of Harmless Score Ranson’s scoring system predicting severity Pancreatitis.
 Methods: A prospecti...

Abstract Objectives The purpose of this study was to comprehensively assess the heterogeneity procedures in diagnostic guidelines for acute pancreatitis and identify gaps limiting knowledge diagnosing disease. Methods A systematic search a number databases performed determine diagnosis patients with severe pancreatitis. were evaluated by AGREE II. Measurement Scale Rate Agreement (MSRA) used (2...

BACKGROUND Proinflammatory and anti-inflammatory cytokines are involved in the pathogenesis of acute pancreatitis. AIMS To measure the serial serum levels of interleukin 10 and interleukin 11 in patients with acute pancreatitis and analyse the relation of these anti-inflammatory cytokines to disease severity. METHODS In 50 patients with acute pancreatitis, the serum concentrations of interl...

DOBBS, R. H. (1935): Acute Pancreatitis in Childhood, Lancet, ii, 989. DUNcAN, N. A. (1948): Pancreatitis due to Ascariasis, Brit. med. J7., i, 905. GALLIE, W. E., and BROWN, A. (I924): Acute Hemorrhagic Pancreatitis Resulting from Roundworms, Amer. J. Dis. Child., 27, I92. GIBSON, J. M., and GIBSON, J. M., JR. (I956): Acute Hemorrhagic Pancreatitis in Childhood, Pediatrics, 48, 486. HERZOG, E....

From a clinical perspective pancreatitis can be broadly categorized as acute, recurrent acute or chronic. It can be further classifi ed according to its effect on the patient as mild or severe, nonfatal or fatal, and also by the presence of sequela such as abscess formation. Histologically, acute pancreatitis is characterized by fi ndings that range from pancreatic edema to necrosis, variable i...

In HIV-seropositive individuals, the incidence of acute pancreatitis may achieve 40% per year, higher than the 2% found in the general population. Since 1996, when combined antiretroviral therapy, known as HAART (highly active antiretroviral therapy), was introduced, a broad spectrum of harmful factors to the pancreas, such as opportunistic infections and drugs used for chemoprophylaxis, droppe...