Copper sulfate is widely used as a fungicide and pesticide. Acute copper poisoning rare but potentially lethal in severe cases. can lead to cellular damage of red blood cells, hepatocytes, myocytes. Toxic effects include intravascular hemolysis, acute tubular necrosis and, rhabdomyolysis. A 76-year-old man presented with vomiting epigastric pain. He had ingested copper-containing (about 13.5 g ...

Acute kidney injury (AKI), formly known as acute renal failure (ARF), is an abrupt and reversible decrease in function indicated by the glomerular filtration rate (GFR). Diclofenac-induced AKI due to toxic effect of it on glomeruli, resulting lesions.
 Furthermore, diclofenac causes autolysis, which increase intracellular osmolarity that leads proximal tubular dilatations. Lipoic acid (LA)...

1. Ortega‐Loubon C, Fernández‐Molina M, Carrascal‐Hinojal Y, Fulquet‐Carreras E. Cardiac surgery‐associated acute kidney injury. Ann Card Anaesth 2016;19:687‐98. 2. Gaffney AM, Sladen RN. Acute kidney injury in cardiac surgery. Curr Opin Anaesthesiol 2015;28:50‐9. 3. Berger MM, Soguel L, Shenkin A, Revelly JP, Pinget C, Baines M, et al. Influence of early antioxidant supplements on clinical evo...

Acute kidney injury (previously known as acute renal failure) is a common complication in hospitalized patients, and its incidence has risen significantly in the past 15 yr. Despite significant technical advances in therapeutics, the mortality and morbidity rates associated with acute kidney injury remain dismally high and have not appreciably improved during the past four decades. Although the...

To assess effects of epidermal growth factor (EGF) and pegylated granulocyte colony-stimulating factor (P-GCSF; pegfilgrastim) administration on the cellular origin of renal tubular epithelium regenerating after acute kidney injury initiated by mercuric chloride (HgCl2 ). Female mice were irradiated and male whole bone marrow (BM) was transplanted into them. Six weeks later recipient mice were ...

this study was carried out to determine the prevalence and type of renal lesions in cattle that were slaughtered at the ghaem (shahriar) and ziaran (ghazvin) abattoirs. a total number of 405 clinically normal cattle were randomly selected and renal samples were taken for histopathological study. the cattle were divided into two groups according to sex, and female groups were divided into two ag...