نتایج جستجو برای: adenomatous polyp
تعداد نتایج: 15992 فیلتر نتایج به سال:
Recent studies have suggested that hyperplastic polyps may be benign precursor lesions for a distinct subset of colorectal tumors. We conducted a clinic-based case-control study to evaluate risk factors for hyperplastic polyps. Cases with hyperplastic polyps (n = 219), adenomas (n = 437), and both types of polyps (n = 138), along with colonoscopy-negative controls (n = 708), were identified at ...
Juvenile (retention) polyps are usually solitary lesions in the colorectum but may be multiple in juvenile polyposis. The association between juvenile polyps and colorectal neoplasia is controversial. We present three patients with juvenile polyposis who had colorectal adenomas or adenomatous epithelium in juvenile polyps at ages 3, 4, and 7 years. In a retrospective study of 57 additional pati...
The concept of the adenoma-carcinoma sequence, as first espoused by Morson et al. whereby the development of colorectal cancer is dependent on a stepwise progression from adenomatous polyp to carcinoma is well documented. Initial studies of the genetics of inherited colorectal cancer susceptibility concentrated on the inherited colorectal cancer syndromes, such as Familial Adenomatous Polyposis...
The genetic and morphological development of colorectal cancer is a paradigm for tumorigenesis. However, the dynamics of clonal evolution underpinning carcinogenesis remain poorly understood. Here we identify multipotential stem cells within human colorectal adenomas and use methylation patterns of nonexpressed genes to characterize clonal evolution. Numerous individual crypts from six colonic ...
OBJECTIVE To determine the association between pericolonic fat and colorectal polyps using CT colonography (CTC). METHODS A total of 1169 patients who underwent CTC and optical colonoscopy on the same day were assessed. Pericolonic fat was measured on CTC in a band surrounding the colon. Visceral adipose tissue volume was measured at the L2-L3 levels. Student's t-tests, odds ratio, logistic r...
To determine whether proliferative patterns in flat rectal mucosal samples can predict the recurrence of adenomatous colorectal polyps, after polypectomy, biopsy specimens from normal looking rectal mucosa were obtained at endoscopy from 55 patients diagnosed for the first time as having adenomatous colorectal polyps. Epithelial cell proliferation was assessed in biopsy specimens through 3H-thy...
We compared clinicopathological characteristics of colorectal polyps, in order to investigate the hypothesis of neoplastic transformation of hyperplastic polyps. Of 4723 colonoscopies performed in our department over four years, 22 patients with 23 mixed hyperplastic polyps (MHAP) were found. These were compared with 61 patients with 86 hyperplastic polyps, 40 with 58 tubular adenomas and 27 wi...
A 42-year-old male patient consulted several times for recurring episodes of bleeding per rectum. An anal source was clinically suspected from the beginning due to the pattern of blood expulsion after passing stools. The patient had been studied for this reason and had undergone two colonoscopies under deep sedation with propofol. Small size hemorroides were observed and different kinds of trea...
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