adipose tissue secretes a large number of adipocytokines such as leptin, resistin, and adiponectin. many of these hormones and cytokines are altered in obese individuals and may lead to disruption of the normal balance between cell proliferation, differentiation, and apoptosis. the aim of our work was to investigate the disturbance of secretion of adiponectin and resistin in de novo and relapse...

_________________________________________________________________ 5 Populärvetenskaplig sammanfattning __________________________________________ 9 List of papers _____________________________________________________________ 11 Abbreviations _____________________________________________________________ 13 Introduction ______________________________________________________________ 15 Breast canc...

conclusions it is speculated that increased insulin resistance and increase in other adipokines such as il-6 may contribute to the decreased serum levels of adiponectin in patients with both cad and t2dm. objectives in this present study, we measured serum adiponectin levels in consecutive cad patients with and without t2dm and investigated whether decreased adiponectin is associated with risk ...

Adiponectin, an adipocyte-derived hormone, exerts pleiotropic biological effects on metabolism, inflammation, vascular homeostasis, apoptosis and immunity. Recently, adiponectin has been suggested to attenuate the progression of human dermal fibrosis. Connective tissue growth factor (CTGF) is induced in keloids and is thought to be participated in the formation of keloid fibrosis. However, the ...

AIMS To clarify predictive values of C-reactive protein (CRP) and high-molecular-weight (HMW) adiponectin for development of metabolic syndrome. RESEARCH DESIGN AND METHODS We conducted a prospective cohort study of Japanese workers who had participated in an annual health checkup in 2007 and 2011. A total of 750 subjects (558 men and 192 women, age 46±8 years) who had not met the criteria of...