Pharmacoeconomic/outcomes research (PE/OR) fellowships have been in existence for more than 10 years in response to the rising demand for expertise in economic evaluation.1-4 The first fellowship in PE/OR began in 19891; however, finding detailed information about these programs is difficult for several reasons. First, quantifying PE/OR programs is a challenge due to their increasing number in ...

the concepts of SIRS and CARS still exist, although the notion that CARS represents a reaction to SIRS has been challenged [3, 4] . In this theme issue of the Journal of Innate Immunity, current knowledge of several aspects of the SIRS and CARS concepts are reviewed in 7 articles; the issue is completed by 3 original articles about these topics. Kumpf and Schumann [5] summarize data on genetic ...

We introduce a new technique that adopts the halo occupation framework for understanding the origin of QSO absorption-line systems. Our initial study focuses specifically on Mg II absorbers. We construct a model of the gaseous content in which the absorption equivalent width Wr is determined by the the amount of cold gas, in the form of discrete clouds, along a sightline through a halo. The two...

A sector condition for two connected deadzone nonlinearities is provided. By introducing an additional non-square operator which exploits their connectivity, a more general set of sector-like matrix inequalities is obtained. This “non-square” matrix inequality condition is applied to an anti-windup (AW) problem in which the AW compensator is not activated until the unconstrained control signal ...

Adaptively weighted Sub-pattern PCA (Aw-SpPCA) for face recognition is presented in this paper. Unlike PCA based on a whole image pattern, Aw-SpPCA operates directly on its sub-patterns partitioned from an original whole pattern and separately extracts features from them. Moreover, unlike both SpPCA and mPCA that neglect different contributions made by different parts of the human face in face ...

The Adjusted Winner procedure is an important fair division mechanism proposed by Brams and Taylor for allocating goods between two parties. It has been used in practice for divorce settlements and analyzing political disputes. Assuming truthful declaration of the valuations, it computes an allocation that is envy-free, equitable and Pareto optimal. We show that Adjusted Winner admits several e...

Background Rheumatoid factor-positive subtype of juvenile idiopathic arthritis (RF+ JIA) is a relatively rare condition (5-7% all cases JIA), but associated with poor prognosis. For these patients (pts), it extremely important to timely prescribe adequate therapy, including biologics (B), prevent rapid progression and early disability. Objectives To analyze in retrospective study the rate usage...

Inspired by the theory of P -and Q-polynomial association schemes we consider the following situation in linear algebra. Let F denote a field, and let V denote a vector space over F with finite positive dimension. We consider a pair of linear transformations A : V → V and A : V → V satisfying the following four conditions. (i) A and A are both diagonalizable on V . (ii) There exists an ordering...

Let K denote a field and let V denote a vector space over K with finite positive dimension. Let End(V ) denote the K-algebra consisting of all K-linear transformations from V to V . We consider a pair A,A ∈ End(V ) that satisfy (i)–(iv) below: (i) Each of A,A is diagonalizable. (ii) There exists an ordering {Vi} d i=0 of the eigenspaces of A such that A Vi ⊆ Vi−1+ Vi + Vi+1 for 0 ≤ i ≤ d, where...