This essay provides an overview of the central theoretical law and economics insights concerning antidiscrimination law across a variety of contexts including discrimination in labor markets, housing markets, consumer purchases, and policing. The different models of discrimination based on animus, statistical discrimination, and cartel exploitation are analyzed for both race and sex discriminat...

law is the follower of social changes and its final main aim is to make law system of relation resulted from. simultaneously by human social improvements in the field of communication in recent decades- which calls the present age the age of communication- a concept names electronic government has formed and has changed the model of general services presentation. the entrance of technical infor...

introduction: a noninvasive method of detecting exposure of phosphatidylserine (ps) on the external surface of the plasma membrane such as nuclear imaging could assist the diagnosis and therapy of apoptosis related pathologies. the most studied imaging agent for apoptosis is annexin v so far. because of limitations of annexin v other agents have been introduced such as small peptides and molecu...

Identification of components present in biological complexes requires their purification to near homogeneity. Methods of purification vary from protein to protein, making it impossible to design a general purification strategy valid for all cases. We have developed the tandem affinity purification (TAP) method as a tool that allows rapid purification under native conditions of complexes, even w...

Market basket analysis (MBA) is a widely used technique for identifying affinities among items that customers purchase together. MBA metrics are support, confidence, and lift. We show that support and confidence may include misleading information about the nature of the affinity, and that lift is the most useful metric. Starting with the MBA, we use the product affinities to predict ways to inc...

A single-step protein affinity purification protocol using Aspergillus nidulans is described. Detailed protocols for cell breakage, affinity purification, and depending on the application, methods for protein release from affinity beads are provided. Examples defining the utility of the approaches, which should be widely applicable, are included.

To learn the molecular mechanism of an enzyme action, first the protein has to be purified. Because of its simplicity and reproducibility, affinity chromatography has become a adopted method throughout the scientific community. Affinity chromatography occupies a unique place in separation technology since it is the only technique which enables purification of almost any biomolecules on the basi...

Acetylation signaling pathways are involved in numerous cellular processes and are used as therapeutic targets in several disease contexts. However, acetylated proteins only represent a minor fraction of the full proteome, and the identification and quantification of acetylated sites remain a technological challenge. Currently, pan-acetyl antibodies are used to increase the abundance of acetyla...