The mechanism by which the angiotensin I (AI) converting enzyme inhibitor SQ20,881 (<GluTrp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) blocks the pressor response to exogenous AI was studied in mo in the intact anesthetized dog. When administered as a single dose 250 times that of Injected AI (250 nmoles/kg) into either the pulmonary or systemic circulation, SQ20,881 produced inhibition of pulmonary conversi...

BACKGROUND Topical hemostatic agents are used to reduce bleeding and transfusion need during cardiothoracic surgery. We report our experience with Arista® AH Absorbable Hemostatic Particles (Arista® AH), a novel plant-based microporous polysaccharide hemostatic powder. METHODS Data were retrospectively collected for patients (n = 240) that received cardiothoracic surgery at our institution fr...

Platelet-activating factor-acetylhydrolase (PAF-AH) is a lipoprotein-associated phospholipase A2 capable of hydrolyzing platelet-activating factor (PAF) and oxidatively modified phospholipids. We studied the plasma- and lipoprotein-associated PAF-AH activity in patients with primary hypercholesterolemia. Thirty-eight unrelated patients with heterozygous familial hypercholesterolemia (HeteroFH),...

34 Because of the tradition of using honey as an antimicrobial medicament, we investigated 35 the effect of natural honey (NH) on Streptococcus mutans growth, viability and biofilm 36 formation compared to an artificial honey (AH). AH contained the sugars at the concentrations 37 reported for NH. NH and AH concentrations were obtained by serial dilution with tryptic soy 38 broth (TSB). Several ...

We sought to determine if verapamil induces frequency-dependent prolongation of atrioventricular nodal conduction in 10 consecutive patients studied in the electrophysiology laboratory. We used a maintenance infusion of verapamil designed to produce plasma concentrations of verapamil in the "therapeutic" range and that did not alter heart rate or blood pressure significantly. Frequency-dependen...

The accurate prognostic stratification of alcoholic hepatitis (AH) is essential for individualized therapeutic decisions. The aim of this study was to develop a new prognostic model to predict liver-related mortality in Asian AH patients. We conducted a hospital-based, retrospective cohort study using 308 patients with AH between 1999 and 2011 (a derivation cohort) and 106 patients with AH betw...

The relationship of albumen height (AH) to the compositions of yolks and embryos in hatching eggs from a young (30 wk of age) broiler breeder flock was evaluated during incubation. On Day 2 of incubation, egg weight, yolk weight, and yolk moisture, lipid, and fatty acid contents were determined in eggs from broiler breeders previously identified as laying eggs of either low or high AH. In addit...

In studies designed to examine the effects of the immune system, recordings of multi-unit electrical activity (MUA) in the central nervous system were made in the preoptic area/anterior hypothalamus (POA/AH) and paraventricular nucleus (PVN) of rats, following sheep red blood cell (SRBC) immunization. Peak increases in POA/AH MUA were observed on the fifth day following SRBC sensitization, the ...

Heterocyclic amines, suspected as cancer initiators, require metabolic activation to exert genotoxicity. The food carcinogen 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ) undergoes activation via N-hydroxylation by cytochrome P450 1A2, followed by O-esterification by N-acetyltransferase. We examined the effects of the Ah locus and acetylator polymorphisms (implicated in human colon and bladder ...

B C, D E % FG AH ! I ; A A% .FG J /=<K%A/?7 L I M N / O ; H % P A M = % .F() B 7(/0 =; Q7 H N-.%& 1/R . S ; A A M T/$ /= R 0 E /: U ;/L NV A ;/L = G W A M N $ % .F ; 2F # :% 2H SCXH %2 NHT M # /= A $ "/Y Z ; [ AH %&/L ; /1%A/\ J N C,% AHI &H ] #) ^ AH %&/ _C, , 0 N-.%A C`/1 ] . : . ; H ;/ a AH b A ; $ % .FO . `c# ; A% %2-. d I ; A/D*e ;% AH f J : # :%& M M U . " g # hc# M &% J N J%2-. d 7(/1 \-...