Successful high-throughput screening requires methods for determining the precision of liquid dispensing. We compared absorbance and fluorescence methods. We found that plate-to-plate variability was large enough to mask the difference in optical methods. When a dual-dye method was used, we found that absorbance and fluorescence gave similar results in 96and 384-well plates. In 1536-well plates...

OBJECTIVE We developed a novel simple microwell plate that allows researchers to culture cells on chips easily without the use of tubes and pumps for studies of cell proliferation, apoptosis and pharmacology. Unlike any other previous design, this device can be put into an incubator directly and maintains cells in an environment with stable temperature, humidity, air pressure, oxygen and CO2 co...

We consider deflections of a thin rectangular elastic plate that is submerged within a Newtonian fluid. The plate is clamped along one edge and supported horizontally over a plane horizontal wall. We consider both external driving, where the clamped edge is vibrated vertically at high frequencies, and thermal driving, where the plate fluctuates under Brownian motion. In both cases, the amplitud...

A capacitor is formed when a level-sensing electrode is installed in a vessel. The metal rod of the electrode acts as one plate of the capacitor and the tank wall (or reference electrode in a non-metallic vessel) acts as the other plate. As the level of the material being measured rises, the air or gas normally surrounding the electrode is displaced by the material’s different dielectric consta...

In this communication, a wideband reconfigurable reflectarray based on reflector-backed active second-order bandpass frequency selective surface (FSS) is presented. The reflector composed of periodic short-circuited parallel plate waveguide (PPW) and the FSS stacked non-resonant metallic elements separated by thin dielectric substrates. By integrating microwave varactors in capacitive layers FS...

Estimations of the bacterial content of air can be more easily made now than a decade ago, with colony formation the method of choice for enumeration of airborne bacteria. However, plate counts are subject to error because bacteria exposed to the air may remain viable yet lose the ability to form colonies, i.e., they become viable but nonculturable. If airborne bacteria exhibit this phenomenon,...

This study examines employee stock options in private entrepreneurial companies. I focus on private U.S. venture-backed firms because they are renowned for the intensity and organizational depth of their stock option grants. Contrary to simple stereotype, however, I show that 27% of U.S. venture-backed firms do not grant stock options to all employees. I seek to explain this by theorizing that ...

In this paper we examine the premarket underpricing phenomenon within a group of venture-backed and a group of non venture-backed initial public offerings (IPOs) using a stochastic frontier approach. Consistent with previous research, we find that venture-backed IPOs are managed by more reputable underwriters and are generally associated with less underwriter compensation. However, unlike other...