Ozone is an atmospheric pollutant that causes lung inflammation and airway hyperresponsiveness. Ozone's effects occur in two distinct phases that are mediated by different populations of eosinophils. In the acute phase 1 day after exposure, mature airway-resident eosinophils alter parasympathetic nerve function that results in airway hyperresponsiveness. At this time point, the severity of hype...

BACKGROUND Treatment of airway compromise in trauma patients is a priority. Basic airway management is provided by all emergency personnel, but the requirement for on-scene advanced airway management is controversial. We attempted to establish the demand for on-scene advanced airway interventions. Trauma patients managed with standard UK paramedic airway interventions were assessed to determine...

OBJECTIVE To determine the extent to which thin-section and volumetric threedimensional CT can depict airway reactivity to bronchostimulator, and to assess the effect of different airway sizes on the degree of reactivity. MATERIALS AND METHODS In eight dogs, thin-section CT scans were obtained before and after the administration of methacholine and ventolin. Cross-sectional areas of bronchi a...

Sheep airway mucus can potently scavenge hydrogen peroxide, an important mediator of airway inflammation. Here, the scavenging activity was identified as a peroxidase produced by goblet cells of the airway epithelium and secreted into the airway lumen. Ovine airway peroxidase activity was purified approximately 100-fold from airway lavage fluid in two steps, using cation exchange and lectin aff...

Difficult airway is a common problem encountered in oro-maxillo-facial surgeries. We describe case where displaced mandibular reconstruction plate obstructing the access to oral cavity. The was further compromised by previous tracheostomy, and limited neck extension owing surgeries radiotherapy. inability of patient swallow increased risk pulmonary aspiration. first line management such should ...

Airway management in craniofacial trauma patients is a challenge for an anesthetist. Treating these patients requires a close interdisciplinary communication and cooperation. Maintaining the airway and oxygenation of the patient is the initial challenge in craniofacial trauma patients. The management of the difficult airway is facilitated and patient's safety improved by following one of severa...

background : we aimed to compare hemodynamic and endocrine alterations caused by stress response due to proseal laryngeal mask airway and endotracheal tube usage in laparoscopic cholecystectomy. methods : sixty-three asa i-ii patients scheduled for elective laparoscopic cholecystectomy were included in the study. patients were randomly allocated into two groups of endotracheal tube and proseal ...

conclusions our study revealed weak correlation between pe/e-vc and cormack-lehane grade, with 87% sensitivity and 30% specificity. therefore, we concluded that sonographic measurement criteria are not accurate in airway evaluations before anesthesia. results it was observed that correlations between the pre-epiglottic space (pe) and cormack-lehane grades i, ii, and iii were weak. correlations ...

Respiratory pathogens and toxins often assault the lung from the airway lumen. Airway epithelia may initiate and amplify inflammation in response to these attacks, but under certain conditions confinement of inflammation to the airway lumen may be beneficial to the host. Accordingly, we hypothesized that airway epithelial polarity allows different responses to basolateral vs apical stimuli that...

Laryngeal mask airway (LMA) was a useful, powerful airway management device for routine pediatric airway management, pediatric difficult airway, and in pediatric emergency situations. Over years, various designs, induction and insertion techniques have been described. LMA provides ease of placement and removal as compared with endotracheal intubation, less traumatism for the respiratory tract, ...