Intercellular signaling is crucial for embryonic patterning, cell specification and tissue induction. Hedgehog (Hh) encodes a secreted signal originally identified in Drosophila (Nüsslein-Volhard and Wieschaus, 1980). Vertebrate family members have been subsequently isolated (Echelard et al., 1993; Ekker et al., 1995; Krauss et al., 1993; Riddle et al., 1993; Roelink et al., 1994). In vivo and ...

Acoustic intensity measurements were conducted on a simple spur gear transmission in a welded steel housing. The radiation efficiency of the housing was computed from the intensity data for the first three harmonics of mesh frequency. Finite element and boundary element methods (FEM/BEM) were used jointly to model acoustics and dynamics of the top plate of the housing. For a simply supported el...

A numerical study of steady-state, fully developed, MHD duct flows is presented for the case of an applied transverse magnetic field and a two-dimensional variation of the flow parameters in the plane perpendicular to the flow direction, with no variations in fluid properties. Solutions are found for (i) rectangular ducts with no obstacles and (ii) rectangular ducts containing thin flat plates,...

For the Generalized Plane Stress (GPS) problem in linear elasticity, we obtain an optimal stability estimate of logarithmic type for inverse determining smooth cavities inside a thin isotropic cylinder from single boundary measurement traction and displacement. The result is obtained by reformulating GPS as Kirchhoff–Love plate-like terms Airy function, using strong unique continuation at plate...

The new species is a member of an apparently monophyletic group within the genus that includes R. flexile, R. walga, R. himanturi, R. burgeri, R. euzeti, R. hawaiiensis, R. urobatidium, R. paratrygoni, R. ditesticulum, R. tetralobatum, R. margaritense, R. biorchidum, and R. spinicephalum. All of these species have bothridia with medial longitudinal septa, a constriction at mid-bothridium, and, ...

INTRODUCTION: Micro Electro Mechanical Systems (MEMS) are fabricated with an in-plane fabrication technology. Out-of-plane structures can be designed to be assembled to provide thermal and electrical isolation from the substrate [1 -3]. These isolations can potentially improve the performance of a range of MEMS devices by decreasing any unwanted coupling effects or parasitic losses from the dev...

levels. This fits well with the observation that the repul-1998). It remains to be seen, however, whether these or 1133.102, 363–375. tions be in mediating guidance decisions at choice points? Another possible site for this mechanism to operate is at the ventral midline of the CNS. In vertebrates, commissural axon crossing of the ventral midline of the spinal cord is regulated by a combination ...

Abstract Fracture behavior of Al-Mn alloy after plastic deformation is studied by electron microscopy. Cracked can mainly caused the lamination Al-Mg plate. Optimized melt treatment main way to solve problem microporosity. Microporosity be eliminated adjusting casting speed and other technological parameters. As a result, during weakened. The rate cracked cans in process reduced subsequently.

The objective of this proposal is to characterize and understand the processes by which the crust within and adjacent to the Northern San Andreas Fault Zone (NSAFZ) deforms over 10s of kyr to several Myr to link coand inter-seismic deformation to that observed geologically. I will use for this task high resolution GeoEarthScope Airborne Laser Swath Mapping (ALSM) and more broadly available lowe...

geometric and material nonlinear behavior of slender webs in i-column girders having stocky flanges under the action of combined lateral and axial loads is investigated. interaction curves corresponding to the application of compressive and shear loads at buckling and ultimate stages for both web plates and column sections are plotted. in addition, the effects of flange and web slenderness rati...