BACKGROUND The incidence of hepatocellular cancer in complicated alcoholic and non-alcoholic fatty liver diseases is on the rise in western countries as well in our country. Vascular adhesion protein-1 (VAP-1) levels have been presented as new marker. In our study protocol, we assessed the value of this serum protein, as a newly postulant biomarker for hepatocellular cancer in patients with a h...

OBJECTIVE Little is known about metabolic factors in cirrhotic patients in China. Therefore, we aimed to quantify the prevalence of both metabolic factors and non-alcoholic steatohepatitis-related liver cirrhosis in China. METHODS The medical records of 1,582 patients diagnosed with liver cirrhosis from June 2003 to July 2013 at Daping Hospital (Chongqing, China) were retrospectively reviewed...

Alcoholic liver disease, a leading cause of morbidity, mortality, and cirrhosis, can range from simple steatosis to hepatocellular carcinoma. Multiple mechanisms such as oxidative stress, mitochondrial dysfunction, and alteration in gut-liver axis have been proposed for the pathogenesis of alcoholic liver disease. Based on different prognostic models, alcoholic hepatitis patients can be stratif...

Alcoholic liver disease, including acute alcoholic hepatitis and alcoholic cirrhosis, is a major cause of morbidity and mortality in the Western world. Abstinence remains the cornerstone of management of all forms of alcoholic liver disease. Recent research, which has elucidated the mechanisms of alcohol-induced liver injury, offers the prospect of advances in the management of alcoholic liver ...

Iron overload disorders can present as non-specific symptoms and develop gradually but, if untreated, be very fatal. The common causes include multiple blood transfusions for chronic anemia increased iron absorption, including hereditary hemochromatosis (HH). HH is one of the usually presents with liver cirrhosis in a setting significantly elevated ferritin transferrin saturation. Alcoholic hep...

Background: Spontaneous bacterial peritonitis (SBP) is one of the most common complications in cirrhosis with ascites, which associated a high mortality. Various studies have shown that prevalence PBS ranges from 20-30% patients and ascites. Not all cases it accompanied by obvious symptoms, makes early diagnosis difficult. Aim: The aims this study were to assess risk factors alcohoolic liver ci...

Background: Cirrhosis is a common hepatological disorder seen in clinical practice. Liver plays an essential role in lipid metabolism, several stages of lipid synthesis and transportation. It is reasonable to expect an abnormal lipid profile in those with severe liver dysfunction Aim: To assess the lipid profile abnormalities in patients with cirrhosis of liver correlate with the severity of ci...