results although a hypocaloric diet could prevent the progression of fat accumulation in liver, the diet composition is another aspect which should be considered in diet therapy of patients with nafld. conclusions several studies assessed the effects of dietary composition on fat storage in liver; however, their findings are inconsistent. most studies focused on the quantity of carbohydrate and...

Since their discovery more than a decade ago microRNAs have been demonstrated to have profound effects on almost every aspect of biology. Numerous studies in recent years have shown that microRNAs have important roles in development and in the etiology and progression of disease. This review is focused on microRNAs and the roles they play in liver development, regeneration and liver disease; pa...

Alcohol is currently recognized as the most prevalent known cause of abnormal human development. Our aim was to investigate the effect of raw garlic on patients suffering from alcoholic liver disease. 20 alcoholic patients and 20 healthy individuals were selected. Both patients and normal individuals were subjected to detailed clinical examination and laboratory investigations. Blood samples we...

The prevalence and incidence of alcoholic liver disease are constantly evolving. Alcoholic liver disease has a wide clinical spectrum. It may progress to cirrhosis and to end-stage liver disease requiring liver transplantation. The histological manifestations range from steatosis without inflammation to liver cell injury and ultimately to fibrosis and cirrhosis. In some cases, the histological ...

Alcoholic and chloroform extracts of E. albaT. purpurea and B. diffusa were screened for antihepatotoxic activity. The extracts were given after the liver was damaged with CCl4. Liver function was assessed based on liver to boy weight ratio, pentobarbitone sleep time, serum levels of transaminase (SGPT, SGOT), alkaline phosphatase (SALP) and bilirubin. Alcoholic extract of E. alba was found to ...

AIMS To determine whether the functional polymorphism -592C>A of the interleukin (IL)-10 gene (IL10) influences the development of alcoholic liver disease or alcoholism in alcoholic Spanish subjects. METHODS The -592C>A IL10 polymorphism was analyzed by the polymerase chain reaction and digestion with restriction enzymes in 257 male alcoholics [161 without alcoholic liver disease and 96 with ...

The patient was a 78-year-old man who had attended our hospital with alcoholic liver cirrhosis as Child-Pugh classification A.

objective(s):non-alcoholic steatohepatitis (nash), is an important component of non-alcoholic fatty liver disease (nafld) spectrum, which progresses to the end stage liver disease, if not diagnosed and treated properly. the disproportionate production of pro- and anti-inflammatory adipokines secreted from fat contributes to the pathogenesis of nash. in this study, the comparative effect of piog...