Published articles have been reprinted with the permission of the copyright holder. Till Charlotte och Moa! Of all knowledge, there is nothing greater than to know that You love me. Abstract Fatty liver has previously often been associated with excessive alcohol consumption. During the last two decades, the interest in fatty liver occurring in non-drinkers i.e. non-alcoholic fatty liver disease...

 The burden of alcoholic liver disease continues to be a major public health problem worldwide. The spectrum of disease ranges from fatty liver to cirrhosis and hepatocellular carcinoma. Alcoholic hepatitis (AH) is a type of acute-on-chronic liver failure and the most severe form of alcoholic liver disease. Severe AH carries a poor short-term prognosis and its management is still challenging, w...

Objective: Non – alcoholic fatty liver disease (NAFLD) is an imageological entity without elevation of liver enzymes. The purpose of this case – control study was to corelate microalbuminuria to Prediabetes with and without NAFLD. Method: This study was done at the Department of Medicine,DR. PSIMS & RF Chinaoutpally, A.P. India between Jan 2012 to Dec 2012. 200 patients (100 cases, 100 controls...

This study was designed to determine whether dietary epigallocatechin-3-gallate (EGCG), the most abundant catechin polyphenol in green tea, can protect the liver from cytochrome P450 2E1 (CYP2E1)-dependent alcoholic liver damage. Compared with an ethanol group, when EGCG was present in the ethanol diet, the formation of a fatty liver was significantly reduced and the serum aspartate transaminas...

Background: Alcoholic cirrhosis is second leading indication for liver transplantation in United States and Europe. The spectrum of alcohol related liver injury varies from simple steatosis to cirrhosis; patients with alcoholic cirrhosis have high prevalence of complications at the time of cirrhosis diagnosis. So there is a need to study the radiology and underlying biochemical changes for earl...

Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) cause significant morbidity and mortality in affected patients and are common causes of liver failure worldwide [1]. NAFLD and ALD are histologically indistinguishable by conventional methods but their disease courses are quite divergent. In particular, ALD patients with steatohepatitis have a more rapid progression to ...

Non alcoholic fatty liver disease occurs in those who don't consume alcohol in amounts considered harmful to the liver. It represents a spectrum of conditions characterized histologically by mainly macrovesicular hepatic steatosis. There are two histological patterns of NAFLD: fatty liver alone and steatohepatitis. In this brief review, clinical and histologic spectrum, natural history, diagnos...

Background/Aim: Non-alcoholic fatty liver disease (NAFLD) refers to the accumulation of hepatic steatosis not due to excess alcohol consumption.It is the most common liver condition in the world.The prevalence of NAFLD is up to 30% in developed countries and nearly 10% in developing nations. The aim of this study is to assess serum alpha-fetoprotein triglyceride, and total cholesterolamong Suda...

AIMS/INTRODUCTION To examine the association between liver histological features and organ-specific insulin resistance indices calculated from 75-g oral glucose tolerance test data in patients with non-alcoholic fatty liver disease. MATERIALS AND METHODS Liver biopsy specimens were obtained from 72 patients with non-alcoholic fatty liver disease, and were scored for steatosis, grade and stage...

Inflammation is a constant in Non-Alcoholic Fatty Liver Disease (NAFLD), although their relationship unclear. In transgenic zebrafish system with chronic systemic overexpression of human IL6 (IL6-OE) we show that inflammation can cause intra-hepatic accumulation triglycerides. Transcriptomics and proteomics analysis the IL6-OE liver revealed deregulation glycolysis/gluconeogenesis pathway, espe...