beside developing strategies, success of organizations depends on alignment of strategies. one of the important functional areas in which companies develop strategies is operation. alignment of operation strategies is called horizontal alignment. the aim of this article is to present a model for alignment of operation strategies. to this end, an original algorithm has been presented by which ho...

Accurately aligning distant protein sequences is notoriously difficult. Since the amino acid sequence alone often does not provide enough information to obtain accurate alignments under the standard alignment scoring functions, a recent approach to improving alignment accuracy is to use additional information such as secondary structure. We make several advances in alignment of protein sequence...

Current ontology alignment practices adopt a centralized approach: the alignment task is carried out by a domain expert, possibly with the help of some ontology alignment tools. In a Peer-to-Peer environment, each end-user (peer) may explicitly or implicitly generate ontology alignments for their own purposes during its own use of the semantic data. This kind of end-user-generated ontology alig...

preset study is conducted to evaluate strategic alignment between business and it in the view of organizational managers. present study has used luftman’s model on strategic alignment maturity and gartlen & shenks’ factors to promote alignment in order to evaluate alignment. research statistical population consists of managers at high education planning and research institute. no sampling is co...

MOTIVATION Many comparative genomics studies rely on the correct identification of homologous genomic regions using accurate alignment tools. In such case, the alphabet of the input sequences consists of complete genes, rather than nucleotides or amino acids. As optimal multiple sequence alignment is computationally impractical, a progressive alignment strategy is often employed. However, such ...

MOTIVATION When routinely analysing protein sequences, detailed analysis of database search results made with BLAST and FASTA becomes exceedingly time consuming and tedious work, as the resultant file may contain a list of hundreds of potential homologies. The interpretation of these results is usually carried out with a text editor which is not a convenient tool for this analysis. In addition,...

We have developed a semiautomated RNA sequence editor (SARSE) that integrates tools for analyzing RNA alignments. The editor highlights different properties of the alignment by color, and its integrated analysis tools prevent the introduction of errors when doing alignment editing. SARSE readily connects to external tools to provide a flexible semiautomatic editing environment. A new method, Pc...

Motivation Whole metagenome shotgun sequencing is a powerful approach for assaying the functional potential of microbial communities. We currently lack tools that efficiently and accurately align DNA reads against protein references, the technique necessary for constructing a functional profile. Here, we present PALADIN-a novel modification of the Burrows-Wheeler Aligner that provides accurate ...