Tropical pulmonary eosinophilia (TPE) is characterized by lung tissue and peripheral blood eosinophilia. Serum total IgE is also markedly increased in TPE. However, an association with asthma or other hypersensitivity conditions has not been described. During the diagnostic workup of three patients eventually confirmed to have TPE, hypersensitivity to the fungus, Aspergillus Fumigatus was found...

Aspergillus, a genus of spore forming fungi found worldwide, affects the respiratory tract in many ways [1, 2]. The spores of this ubiquitous mould are dispersed by wind in the atmosphere and inhalation is the primary route of access in almost all forms of aspergillosis. The spectrum of Aspergillus-associated respiratory disorders comprises three well defined clinical categories (table 1): alle...