Mediators released during inflammatory response play an essential role in eliminating microbes or microbial products. However, the uncontrolled release of cytotoxic substances characterized by extensive inflammation may adversely affect normal tissues. Under such conditions it is important to manage the hyperinflammation in order to change the clinical manifestations of the disease. Accordingly...

morbidity and mortality in the world. About 2.5—3% of the world’s population suffers from this disease, a proportion which, in some countries, can reach 7% or more. Hyperglycemia leads to metabolic disorders and various complications. There is increasing evidence indicating that enhanced production of free radicals may be an important contributing factor in the complications seen in diabetes. S...

objective: gut–brain axis (gba) is very important in creation and modulation of gastrointestinal problems. aloe vera gel has gastroprotective properties. the purpose of this study was to evaluate the effect of aqueous extract of aloe vera leaves on the gastric acid secretion and brain and intestinal water content following acetic acid gastric ulcer induction. materials and methods: gastric ulce...

Chemoprevention Aloe vera DMBA Skin papillomagnesis

Aloe vera is considered as a cosmeceutical herb i.e. a blend of cosmetic and pharmaceutical product. The gel from its leaves finds a wide range of cosmetic and therapeutic applications which include anti-wrinkle creams, moisturizers, sunscreens, haircare products and wound healing, treatment of burns, frostbite, inflammation, diabetes and cancer. It is also used as protective against radiation ...

removing the bacteria, including enterococcus faecalis, from the root canal is one of the important aims in endodontic treatment.we aimed to compare the antibacterial activity of chlorhexidine with two natural drugs. the antibacterial activities of three different propolis extracts (alcohol concentrations: 0, 15, 40%) and aloe vera gel on e. faecalis were compared using three methods: disk diff...

In view of the increasing demand of value added herbal products, an attempt was made to produce a functional fermented Aloe vera based herbal wine. The wine was evaluated for effect on probiotics and food borne pathogens. Aloe vera gel, supplemented with sugar proved to be a good medium for the growth of Saccharomyces cerevisiae for making the Aloe vera wine. The wine was found to be similar to...

Aloe vera L. (syn. A. barbadensis Miller.) is a perennial succulent plant belonging to the Liliaceae family. The plant is known traditionally as the “healing plant” and is claimed to possess wound-healing, burn-healing, immunomodulatory, anti-inflammatory, anti-oxidant, antiallergic, anti-diabetic, and UV protective properties. Due to these therapeutic properties A. vera is being used in a vari...

The gels of Aloe species contain immunomodulatory components such as aloctin A and acemannan. Most studies on these gels were performed in in vitro cell culture systems. Although several studies examined their immunomodulatory activity in vivo, the route of administration was intraperitoneal or intramuscular. Here, we evaluated the in vivo immunomodulatory activity of processed Aloe vera gel (P...

The importance and use of herbal remedies (turmeric, tulsi, amla and aloe vera etc.) has been reviewed systematically. Turmeric (curcumin), acts as an antioxidant, antimutagenic, antiinflamatory and antimicrobial agent and protect liver against a variety of toxicants. Tulsi (eugenol) have anticancer properties, reduced blood glucose levels, total cholesterol levels and promotes immune system fu...