It is well known that type 2 diabetes an endocrine disease. Among glucose-lowering medications, α glucosidase which a membrane bound enzyme at the epithelium of small intestine catalyses cleavage glucose from disaccharide are effective for delaying absorption. i.e., inhibitors delay absorption ingested carbohydrates, reducing postprandial glucose. Pancreatic α-amylase key in digestive system an...

Alpha thalassemia (α-thal) is relatively common worldwide. Most carriers are defective in either one or two alpha globin genes out of four functional ones, with deletions being more common than point mutations. The hematologic features are very important for the selection of the appropriate molecular tests while determining the genotype. The aim of this study was to compare hematologic features...

Inhibition of α-amylase is an important strategy to control post-prandial hyperglycemia. The present study on Ruellia tuberosa, known as traditional anti-diabetic agent, is being provided in silico study to identify compounds inhibiting α-amylase in rat and human. Compounds were explored from PubChem database. Molecular docking was studied using the autodock4. The interactions were further visu...

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In the recent original research published on International Journal of Fertility and Sterility the association between tumor necrosis factor-alpha (TNF-α) genetic polymorphisms and endometriosis in 150 Iranian patients suffered this disease. The authors notably found a lower frequency of TNF-α -863C/A allele A among the affected patients in comparison with healthy women, although this difference...

Alpha-thalassemia (α-thal) is a disorder caused by the deletion of single or double α-globin genes, and/or point mutations in the α-globin genes. There are 2 common types of α-globin genes; HBA2 and HBA1. Recently, it has been discovered that the HBA2 gene is replaced by a unique HBA12 gene convert in 5.7% of the Saudi population. The α-globin genes have been emerging as a molecular target for ...

Transforming growth factor alpha (TGF-α) is a protein that in humans is encoded by the TGFA gene. As a member of the epidermal growth factor (EGF) family, TGF-α is a mitogenic polypeptide. The protein becomes activated when binding to receptors capable of protein kinase activity for cellular signaling. TGF-α is a transforming growth factor that is a ligand for the epidermal growth factor recept...

The 3-dimensional coordinates of alpha-carbon atoms of proteins are used to distinguish the protein structural classes based on recurrence quantification analysis (RQA). We consider two independent variables from RQA of coordinates of alpha-carbon atoms, %determ1 and %determ2, which were defined by Webber et al. (2001). The variable %determ2 is used to define two new variables, %determ21 and %d...

A bstract We propose a novel procedure of assigning pair non-unitary topological quantum field theories (TQFTs), TFT ± [ $$ \mathcal{T} T rank 0 ], to (2+1)D interacting \mathcal{N} N = 4 superconformal theory (SCFT) 0, i.e. having no Coulomb and Higgs branches. The arise from particular dege...

Let p $p$ be a fixed prime. We show that the number of isomorphism classes finite rings order n $p^n$ is α $p^\alpha$ , where = 4 27 3 + O ( 5 / 2 ) $\alpha =\frac{4}{27}n^3+\mathnormal {O}(n^{5/2})$ . This result was stated (with weaker error term) by Kruse and Price in 1969; problem with their proof pointed out Knopfmacher 1973. also commutative β $p^\beta$ $\beta =\frac{2}{27}n^3+\mathnormal...