نتایج جستجو برای: alzheimers disease ad
تعداد نتایج: 1553203 فیلتر نتایج به سال:
Alzheimer’s disease (AD) is the most common form of dementia in the elderly. AD is characterized by senile plaques and neurofibrillary tangles (NFTs) comprised of amyloid-β protein (Aβ) deposits and hyper-phosphorylated tau protein (p-tau), respectively. Oxidative stress-induced neuronal damage is also involved in AD pathogenesis. In the 1970s, studies showed increased levels of aluminum (Al) i...
people with alzheimer disease (ad) have decreases in brain cell function that may increase their risks as drivers. the changes in brain cells affect memory (at first, short-term memory and then much later, long-term memory) and other thinking functions. in addition, people with early ad, though often very functional in many areas of life, may not be as competent behind the wheel of a car as tho...
Introduction: Alzheimer disease (AD), known to be a leading cause of dementia that causes heavy social and financial burdens worldwide, characterized by progressive loss of neurons and synaptic connectivity after depositions of amyloid-β (Aβ) protein.AD manifests as an impaired ability to comprehend or use words, poor coordination and gait, and impaired executive functions in the realms of plan...
Alzheimer disease (AD) is a progressive neurodegenerative brain disorder which plays an important role in neural cell destruction and as a result it causes memory loss in the patients. This disease is also the most common type of dementia which doesn’t completely respond to medical treatments so no certain cure is available. Recent studies show the advantages of using stem cells (SCs) in ...
S eeking a better understanding of vascular contributions to Alzheimer’s disease (AD), the National Institutes of Health (NIH) announced on March 14 the launch of the Molecular Mechanisms of the Vascular Etiology of Alzheimer’s Disease (M2OVE-AD) Consortium, a team-science venture to build a nuanced model of AD that will more accurately reflect its many causes and pathways. Scientists have long...
TheAlzheimer’s DiseaseNeuroimaging Initiative (ADNI) is an ongoing, longitudinal, multicenter Conflicts of intere *Corresponding au 1552-5260/$ see fro doi:10.1016/j.jalz.201 study designed to develop clinical, imaging, genetic, and biochemical biomarkers for the early detection and tracking of Alzheimer’s disease (AD). The study aimed to enroll 400 subjects with early mild cognitive impairment...
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background: alzheimer’s disease (ad) is the most common type of dementia. demonstrating the modifiable risk factors of ad can help to plan for prevention of this disease. the aim of the current review was to characterize modifiable cardiovascular risk factors of ad using existing data and determine their contribution in ad development in iran and the world. methods: the systematic search was do...
background: alzheimer’s disease (ad) is one of the most important neurodegenerative disorder. anti‑cyclic citrullinated peptide (anti‑ccp) may all be involved in the development of vascular disease such as ad. the aim of this study is detection of seropositivity for anti‑ccp antibody in ad patients. methods: in our study, 30 patients with ad and 29 healthy controls (age and‑sex matched) were re...
This paper describes a study of the effects of variation of synaptic connectivity in a thalamo-cortical circuitry using a neural mass model. The oscillatory behaviour of the model output is assessed within the alpha frequency band. The model presented here is a modification of an existing model involving the introduction of biologically plausible synaptic connectivities as well as synaptic stru...
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