نتایج جستجو برای: aml m7
تعداد نتایج: 13547 فیلتر نتایج به سال:
Acute myeloid leukemia (AML) is a disease characterized by neoplastic transformation and abnormality of progenitor cells differentiation from cells. In AML there heterogeneous in hematopoietic cells, this has been identified affects the balance between proliferation, survival body Mutation FMS-like tyrosin kinase 3 (FLT3) gene causes overexpression which one most often found mechanism that coul...
The U.S. Geological Survey has estimated a 99% chance of magnitude 6.7 earthquake in California the next 30 years from 2008. In this paper, Fourier transform, mode analysis and commensurability analysis are used to study cycle predict future strong earthquake. The shows that is most likely to occur 2019, prediction was sent relevant institutions of United States 2018. July 2019 an M7.1 oc...
Genetic aberrations contribute to acute myeloid leukemia (AML). However, half of AML cases do not contain the well-known aberrations detectable mostly by cytogenetic analysis, and these cases are classified as normal karyotype AML. Different outcomes of normal karyotype AML suggest that this subgroup of AML could be genetically heterogeneous. But lack of genetic markers makes it difficult to fu...
Treated secondary acute myeloid leukemia: a distinct high-risk subset of AML with adverse prognosis.
Secondary acute myeloid leukemia (s-AML) includes therapy-related AML and AML evolving from antecedent hematological disorder (AHD). s-AML arising after treating AHD likely represents a prognostically distinct, high-risk disease category. In this study, treated s-AML (ts-AML) was defined by: (1) prior diagnosis of myelodysplasia, myeloproliferative neoplasm, or aplastic anemia and (2) at least ...
Acute myeloid leukemia (AML) is a severe blood malignancy associated with high relapse rate. The current clinical chemotherapy typically perplexed serious side effects. Here, A6 peptide-tagged, small and reduction-sensitive polymersomal vincristine sulfate (A6-cPS-VCR) reported as novel, smart specific treatment for CD44 positive AML. A6-cPS-VCR stably loaded 3.3 wt% VCR displays size of ≈ 31 n...
background: the conventional chemotherapeutic regimens which applied for treatment of acute myeloid leukemia (aml) mostly target tumor bulk but not leukemic stem cells (lscs). aberrant expression or activation of mediators such as osteopontin (opn) or pi3k/pten/akt/mtor pathway plays a key role in making prone to develop leukemia. preventing or treating cancer by curcumin (cur) has been suggest...
background: acute myeloid leukaemia (aml) is a cancer of blood-forming cells in bone marrow. c-kit gene is a receptor tyrosine kinase class iii (rtk) that is expressed by early hematopoietic progenitor cells and plays an important role in hematopoietic stem cell proliferation, differentiation and survival. it is known that c-kit is a proto-oncogene and the activating c-kit mutations are likely ...
Concurrent development of acute myeloid leukemia (AML) and chronic lymphocytic (CLL) is very rare. We present a case simultaneous CLL AML in patient with no prior exposure to cytotoxic agents or irradiation.
Background/aim The chromosome translocation t(8;19)(p11;q13) has been reported in only six acute myeloid leukemia (AML) patients. We here present the genetic and clinical features of seventh AML case with this aberration. Materials methods Cytogenetic molecular investigations were performed on leukemic bone marrow cells from a patient therapy-related AML. Results A was found leading to an in-fr...
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