Psychogenic amnesia is a complex disorder characterised by a wide variety of symptoms. Consequently, in a number of cases it is difficult distinguish it from organic memory impairment. The present study reports a new case of global psychogenic amnesia compared with two patients with amnesia underlain by organic brain damage. Our aim was to identify features useful for distinguishing between psy...

We report a patient presenting with episodes of transient amnesia, some with features suggestive of transient global amnesia (TGA), and some more reminiscent of transient epileptic amnesia. Investigation with neuroimaging revealed an intrinsic lesion in the right amygdala, with features suggestive of low-grade neoplasia. We undertook a systematic review of the literature on TGA and brain tumour...

We present evidence that certain learning parameters can make a memory, even a very recent one, become independent of the hippocampus. We confirm earlier findings that damage to the hippocampus causes severe retrograde amnesia for context memories, but we show that repeated learning sessions create a context memory that is not vulnerable to the damage. The findings demonstrate that memories nor...

Studies of retrograde amnesia have focused on autobiographical memory, with fewer studies examining how non-autobiographical memory is affected. Those that have done so have focused primarily on memory for famous people and public events-relatively limited aspects of memory that are tied to learning during specific times of life and do not deeply tap into the rich and extensive knowledge struct...

1. Ten postcards were shown to groups of ten to twenty patients over 60, 90 or 270 min after intravenous injection of saline, diazepam (10 and 20 mg), flunitrazepam (1 and 2 mg) and lorazepam (4 mg). 2. Incidence of amnesia was estimated by the patients' ability to recall or recognize these cards and to recall various other incidents in the para-anaesthetic period. 3. The use of a dummy confirm...

Introduction: Drugs of abuse such as nicotine and morphine used systemically by addicts produce their effects via the mesolimbic dopaminergic pathway. Furthermore, evidence indicates that some behavioral effects of nicotine and morphine are mediated by nitric oxide (NO). Based on these observations, the aim of the present study was to investigate the effects of intra-nucleus accumbens (NAc) ...

Amnesia can result from damage to either the midline diencephalon or the medial temporal lobe. An important related question has been whether these two forms of amnesia result in similar or different kinds of memory impairment. Earlier studies raised the possibility that differences might exist in the rate of forgetting within long-term memory, specifically, that the forgetting rate is normal i...

The present study was designed to investigate the effect of captopril (20mg kg , i.p.) angiotensin 1 converting enzyme (ACE) inhibitor in learning and memory and on scopolamine (3mg kg , i.p), sodium nitrite 1 (75 mg kg , i.p.) and BN52021 (15mg kg , i.p.) a platelet activating factor (PAF) receptor antagonist, induced 1 1 amnesia in mice using water maze test. All the agents were administered ...