AIM To estimate and compare pubertal growth timing and intensity in height, Tanner stage markers and testis volume. SUBJECTS AND METHODS Data on height, genital stage, breast stage and pubic hair stage, testis volume and menarche in 103 boys and 74 girls from the Edinburgh Longitudinal Growth Study were analysed. The SITAR model for height and a novel mixed effects logistic model for Tanner s...

In this paper, using timber sale auctions in Oregon, we study the merger effects within a general framework where bidders are heterogeneous and entry is endogenous. We propose an entry and bidding model within the affi liated private value (APV) framework and with heterogeneous bidders, and establish existence of the entry equilibrium and existence and uniqueness of the bidding equilibrium with...

We have carried out a precision of the parity-violating asymmetry APV in the scattering of longitudinally polarized electrons off electrons in a liquid hydrogen target. The measurement was performed with the 50 GeV beam line at SLAC. The final result with the full data set collected in three production runs is APV = −131 ± 14 (stat) ±10 (syst) parts per billion. The result leads to new limits o...

The V82F/I84V double mutation is considered as the key residue mutation of the HIV-1 protease drug resistance because it can significantly lower the binding affinity of protease inhibitors in clinical uses. In the current work, the binding of amprenavir to both of the wild-type and the drug-resistant V82F/I84V mutant of the HIV-1 protease was investigated by molecular dynamics (MD) simulations ...