Androgens are steroid hormones that are secreted primarily by the testis, and testosterone is the principal androgen secreted. Its primary function is to regulate the differentiation and secretory function of male sex accessory organs. Androgens also possess protein anabolic activity that is manifested in skeletal muscle, bone, and kidneys. As a class, androgens are reasonably safe drugs, havin...

Elective tonsillectomy remains one of the most commonly performed operations in otolaryngology, with postoperative hemorrhage (PTH) being the most significant potential complication. Anecdotal evidence among ENT Surgeons suggested that bodybuilding athletes may be at increased risk of suffering from PTH, a notion corroborated by a recent case report, regarding primary PTH. The problem has been ...

The title compound, C20H28O2, is a steroid with strong anabolic properties. The present solvent-free form crystallizes with two mol-ecules per asymmetric unit. In the crystal, both mol-ecules are involved in the formation of O-H⋯O hydrogen-bonded chains which extend along the b-axis direction.

the aim of the present study was to investigate the effects of anabolic steroid stanozolol along with eight weeks of resistance training on structural changes in male rats' liver tissue. for this purpose, 28 male adult wistar rats (age: 12 weeks old and 228.53±7.94 g body weight) were randomly assigned to four groups: group 1: control+placebo (n=7), group 2: resistance training+placebo (n=...

The effects of phenformin and ethyloestrenol and phenformin and stanozolol on the clinical state, plasma fibrinolytic activity, and fibrinogen-fibrin-related antigen (F.R.-antigen) were compared with placebo in 13 patients with cutaneous vasculitis. Eight patients showed considerable clinical improvement when taking phenformin and an anabolic steroid; an impaired fibrinolytic activity before tr...

Anabolic steroids remain popular among body builders and power athletes despite numerous warning about their side effects. A case of spontaneous rupture of the anterior cruciate ligament is reported in a bodybuilder taking steroids. While there are many published reports of tendon rupture associated with steroid intake, the authors could find no report relating to ligament disruption.

Peliosis hepatis is a rare condition that can cause hepatic hemorrhage, rupture, and ultimately liver failure. Several authors have reported that peliosis hepatis develops in association with chronic wasting disease or prolonged use of anabolic steroids or oral contraceptives. In this report we describe a case in which discontinuation of steroid therapy improved the condition of a patient with ...

Anabolic androgenic steroids are being more popular between bodybuilders and people who using gym to enhance their physiques. However, according the increase of laws prohibiting sales these substances without physician prescription, route getting administration practices have become dangerous. include many synthetic derivatives testosterone its play a significant role in medical treatment. Thes...

Haematological and hepatic effects of testosterone/anabolic steroid self-administration were investigated in five power athletes during 26 weeks of training. During steroid administration blood haematocrit had increased 9.6% (p less than .05) in the study group (n = 5), but not in the control group (n = 6). This erythropoietic phenomenon was supported by increased (p less than .05) RBC and unch...

High doses of anabolic androgenic steroid are associated with changes in personality, e.g. increased aggression and irritability, behavioural changes that may be linked to structural changes in the hippocampus. In this in vivo study we demonstrate acute effects of a single injection of 19-nortestosterone on proteins that play a major role in molecular plasticity at synaptic connections. The ste...