Postoperative nausea and vomiting (PONV) are major problems after gynaecological surgery. We studied 40 patients undergoing total abdominal hysterectomy, allocated randomly to receive opioid-free epidural-spinal anaesthesia or general anaesthesia with continuous epidural bupivacaine 15 mg h-1 or continuous bupivacaine 10 mg h-1 with epidural morphine 0.2 mg h-1, respectively, for postoperative ...

Respiratory adverse events are one of the major causes of morbidity and mortality in paediatric anaesthesia. Aside from predisposing conditions associated with an increased risk of respiratory incidents in children such as concurrent infections and chronic airway irritation, there are adverse respiratory events directly attributable to the impact of anaesthesia on the respiratory system. Anaest...

A two-compartment model of temperature distribution estimates the core compartment to occupy 66% of body mass at rest, while the peripheral compartment comprises the remainder. General anaesthesia impairs thermoregulation by central and peripheral actions. Peripheral vasodilatation accelerates heat transfer from the core to peripheral compartment causing the core compartment to cool and expand ...

1 Grady RE, Horlocker TT, Brown RD, the Mayo Perioperative Outcomes Group. Neurologic complications after placement of cerebrospinal fluid drainage catheters and needles in anesthetized patients: implications for regional anaesthesia. Anesth Analg 1999; 88: 388–92 2 Chater SN, Greig AJ, Sugden JC. Epidural anaesthesia in the presence of a cerebral tumour. Anaesthesia 1987; 42: 433–4 3 Hilt H, G...

Chloral hydrate, pentobarbitone and urethane were evaluated and compared for onset, duration and depth of anaesthesia, cardiovascular and respiratory effects, nociception and mortality in adult male rats. Chloral hydrate (300 and 400 mg/kg) severely depressed the cardiovascular and respiratory systems. Duration of anaesthesia was linearly related to dose, and anaesthetic depth and analgesia wer...

INTRODUCTION The use of Regional Anaesthesia and Nerve Blocks is becoming more popular and recognized as an effective means for providing anaesthesia for minor surgery. When used optimally, Regional Anaesthesia and local blocks can provide ideal operative conditions. Successful outcome of the technique depends on injection of the local anaesthetic solution as near the target nerve as possible. ...

a 53-year-old male was referred to our department for refractory primary hypertension. despite high doses of 6 anti-hypertensive drugs, ambulatory monitoring of blood pressure (bp) revealed a mean bp of 160/90 mmhg. under local anaesthesia, renal denervation with radiofrequency was performed supported by high-resolution 3d angiography, which helped confirm the position of the applications in a ...

Close co-operation between obstetricians and obstetric anaesthesia providers is crucial for the safety and comfort of parturients, particularly in low-resource environments. Maternal and foetal mortality is unacceptably high, and the practice of obstetric anaesthesia has an important influence on outcome. Well-conducted national audits have identified the contributing factors to anaesthesia-rel...

Pneumocephalus is a commonly encountered entity in patients of head trauma and post-op cases neurosurgery, however it rarely observed after spinal anaesthesia.
 It presents orthostatic hypotension associated with severe headache, nausea vomiting. We report case pneumocephalus following anaesthesia administered for open hernia repair.
 The proposed mechanisms secondary to tapping are t...

Neurotoxicity of anaesthetics have become one the most discussed problems in paediatric anaesthesiology. The experimental studies on animal models shown that used general anaesthesia should an influence neurodegenerative processes, neuroapoptosis and irregulated death neuronal cells. Because this fact, scientists are trying to discover possibilities how minimize adverse effects revise other alt...