khāleq mirzāzādeh is a great ctitic and researcher in tajikistan. he was familiar with sa‘di’s works, especially golestān and boustān , from his teen years; and he created estimable researches about sa‘di through studying of and searching in his works. it should be mentioned that there are worthwhile researches done in tajikistan in relation to sa‘di’s eventful life and his literary heritage. t...

Hypertext constitutes a new way to communicate and think about information. Hypertextual nonsequentiality offers us new ways to analyze the world and facilitates access to philosophical activity to thousands of new social actors. Hypertext is democratising thought and enabling debates between different widely dispersed people. This paper considers hypertext’s role inside new social, scientific ...

Words, Thoughts and Theories argues that infants and children discover the physical and psychological features of the world by a process akin to scientific inquiry, more or less as conceived by philosophers of science in the 1960s (the theory theory). This essay discusses some of the philosophical background to an alternative, more popular, “modular” or “maturational” account of development, di...

We have expressed recombinant RNase P protein from Escherichia coli in high yield. A hexahistidine sequence at the amino terminus allowed protein purification in a single step. Mass spectrometry confirmed the molecular weight of the purified protein and indicated a purity of > 95%. Protein functionality was demonstrated by reconstitution of active holoenzyme.

Site-specific fluorescent labeling of proteins in vivo remains one of the most powerful techniques for imaging complex processes in live cells. Although fluorescent proteins in many colors are useful tools for tracking expression and localization of fusion proteins in cells, these relatively large tags (>220 aa) can perturb protein folding, trafficking and function. Much smaller genetically enc...

BACKGROUND Making peptide pharmaceuticals involves challenging processes where many barriers, which include production and manufacture, need to be overcome. A non common but interesting research area is related to peptides with intracellular targets, which opens up new possibilities, allowing the modulation of processes occurring within the cell or interference with signaling pathways. However,...

Recombinant clathrin protein fragments form assemblies that template gold nanocrystals in an array across the latticed surface. The nanocrystals exhibit unusual anisotropic morphologies with long range ordering, both of which are dependent upon the presence of a hexahistidine tag on the clathrin heavy chain fragments.

meister eckhart is one of the christian mystics that christian orthodoxy and catholic church accused his thoughts in medieval ages and named him heretic. most important themes that disparate the theism of eckhart from his christian predecessors are belief to godhead beyond god, denial of possibility of knowing god, innovations about trinity, belief to apophatic theology and etc. he defended of ...

Al-Farabi adalah seorang ilmuan dan filsuf muslim terkemuka, pemikirannya banyak dirujuk oleh berbagai kalangan, terutama di lingkup akademik dengan disiplin. Pemikiran filsafatnya dipengaruhi pemikiran filsafat Yunani. Salah satu yang saat ini masih relevan untuk dikaji tentang konsep akal bertingkat, dimana mengkonsepsikan ke dalam sepuluh tingkatan. al-farabi bertingkat sedikit perseptif neu...