Primary breast sarcomas are very rare entities, accounting for 0.04% of all malignant neoplasms. Angiosarcoma of breast is infrequent and is an endothelial malignant tumor with bad prognosis because of the frequency of metastasis and recurrence. We present a case of a 30-year-old female who presented with an ulcerated left breast lesion which on further workup revealed to be a primary angiosarc...

We describe a 78-year-old Japanese patient with angiosarcoma on the scalp. Interestingly, immunohistochemical staining revealed this tumor as positive for matrix metalloproteinase 9 (MMP-9). After conventional therapy for angiosarcoma with surgical treatment and radiation therapy, we intravenously administered docetaxel at 40 mg/m(2) body surface area together with oral administration of 17.5 m...

Angiosarcoma of the breast is rare and has a poor prognosis due to its aggressive nature. This is a report of two patients with mammary angiosarcomas, each with different clinical presentations, and at either end of the age spectrum. One is an 18-year-old woman who presented with a rapidly enlarging breast mass, and the other a 72-year-old woman whose breast mass was found during screening mamm...

The authors report a unique case in which an angiosarcoma arose from skeletal haemangiomatosis in a 72 year old man. This patient had a history of atomic bomb irradiation more than 50 years ago. Radiographically, the patient had multiple sclerotic foci of benign haemangiomas in the pelvis, the sacrum, and the left femur. The patient developed a high grade angiosarcoma in the left pubic bone. It...

We present the case of a 41-year-old woman who presented with chest pain. CT for possible pulmonary embolism showed a mass filling the left main pulmonary artery, with imaging features suggestive of pulmonary angiosarcoma. Open thoracotomy for excision of the mass revelaed no mass, only evidence of a chronic pulmonary thrombus of the left pulmonary artery. We conclude that the radiologic featur...

Introduction Primary cardiac tumors are rare, and approximately 25% of which are malignant. Primary cardiac angiosarcoma, which is a rapidly progressing tumor, is the most common malignant tumor of cardiac origin. It is associated with a poor prognosis and median survival time of 3 to 6 months. We report a case of 61-year-old woman who had a history of unknown cause of pericardial effusion 7 mo...

Malignant vascular tumors are rare and angiosarcomas of the breast in patients under 21 years of age are exceedingly uncommon. In this report an angiosarcoma in the breast of a 14-year-old girl is described. She died nine months after mastectomy with recurrent disease in the bones and the contralateral breast. The etiology of most primary angiosarcomas is unknown. Secondary angiosarcomas can de...

An unusual case of bilateral primary pleural angiosarcoma with an immunophenotype of lymphangioendothelial lineage is described. Pleural angiosarcoma is a highly malignant neoplasm for which there is currently no standard of care. A comprehensive immunophenotypic characterization established a lymphangioendothelial lineage. A morphoproteomic analysis was also performed to identify the proteins ...

and soft tissue, and commonly metastasizes to the lungs, showing multiple nodules. The metastatic lung lesions rarely cavitate(1-5), though a angiosarcoma with cavitary metastasis can be complicated by hemopneumothorax(1-5). Metastatic lung lesions showing both cavities and pulmonary hemorrhage on high resolution CT have not, however, been reported. We describe a case of angiosarcoma of the sca...

Angiosarcoma (AS) is a rare and aggressive vascular neoplasm with very poor prognosis. Patients with extensive cutaneous AS who are not surgical candidates have very limited options since there is no standard treatment. Treatment options include radiation, chemotherapy, and angiogenesis inhibitor with varying success rates. Here, we report a case an 88 year old patient with extensive scalp angi...