lipid oxidation has adverse effect on food deterioration and human health. the antioxidant activity of fennel seed extracts (fse) was evaluated by synthetic antioxidant. its oxidative stability was compared in olive oils in concentrations of bha (75 ppm), bht(75 ppm) and  1:1 bha to bht ratio. peroxide (pv), p-anisidine (av) and totox values were evaluated to assess the extent of oil deteriorat...

Commercially available fish oil supplements (FOS) are rich in n-3 polyunsaturated fatty acids (n-3 PUFAs) and have been prescribed as complementary therapy to reduce symptoms many inflammatory skin diseases. The objective of this study was assess the PUFAs content, oxidative stability investigate inhibitory effects on immortalized human keratinocytes (HaCaT) cell growth FOS commercialized Brazi...

A 2,4-diarylquinoline derivative, 2-(4-chlorophenyl)-4-(3,4-dimethoxyphenyl)-6-methoxy-3-methylquinoline, was synthesized in a conventional two-step procedure from p-anisidine, p-chlorobenzaldehyde and methyl isoeugenol as available starting reagents through sequence of BF3·OEt2-catalyzed Povarov cycloaddition reaction/oxidative dehydrogenation aromatization processes under microwave irradiatio...

Ko143 is a tetracyclic, synthetic analog of the fungal metabolite fumitremorgin C. potent and specific inhibitor membrane-bound efflux transporter ABCG2, it reverses ABCG2-mediated drug resistance in cancer cells. Here, we describe an improved synthesis that relies on highly selective, substrate-controlled reduction imine formed Bischler–Napieralski reaction with amide derived from 6-methoxy-l-...

2,4-Dimethoxyaniline hydrochloride, the hydrochloride salt of the dye intermediate 2,4-dimethoxyaniline, was selected for bioassay by the National Cancer Institute because of the increased incidence of bladder cancer among dye manufacturing industry workers. Aromatic amines are one of several classes of chemicals thought to contribute to the increased cancer risk in this industry. A bioassay fo...

st st between 1 of January 2004 and 31 of December 2013 is presented. This was a descriptive retrospective study aimed at establishing the acceptance, safety and effectiveness in our population. Information on socio-demographic characteristics, source of primary information, complications and accidental pregnancies were obtained from clients. Case files entered into Microsoft excel and analyzed...