Purpose: To investigate the differences in macular and nevre fiber layer thicknesses between amblyopic and fellow eyes. Method: One hundred and twenty two eyes of 61 patients were enrolled for this study. All patients underwent complete ocular examination, cover test, prism test and also RNFL, macular thickness measurements (CMT; central macular thickness, TMT; total macular thickness) were obt...

Amblyopia is usually considered to be a deficit in spatial vision. But there is evidence that amblyopes may also suffer specific deficits in motion sensitivity as opposed to losses that can be explained by the known deficits in spatial vision. We measured sensitivity to visual motion in random dot displays for strabismic and anisometropic amblyopic monkeys. We used a wide range of spatial and t...

PURPOSE To test the hypothesis that eyes with amblyopia may have thicker retina, retinal nerve fiber layer thickness (RNFLT) was investigated in patients with unilateral amblyopia. METHODS Thirty-eight patients with unilateral amblyopia were studied. Among them, 20 patients had amblyopia with strabismus and 18 had refractive amblyopia without strabismus. Nineteen of 38 had anisometropia of 2....

PURPOSE. To determine the prevalence of amblyopia and strabismus in young Singaporean Chinese children. METHODS. Enrolled in the study were 3009 Singaporean children, aged 6 to 72 months. All underwent complete eye examinations and cycloplegic refraction. Visual acuity (VA) was measured with a logMAR chart when possible and the Sheridan-Gardner test when not. Strabismus was defined as any manif...

Amblyopia is a neurological disorder of vision that follows abnormal binocular interaction or visual deprivation during early life. Previous studies have reported multiple functional or structural cortical alterations. Although white matter was also studied, it still cannot be clarified clearly which fasciculus was affected by amblyopia. In the present study, tract-based spatial statistics anal...

Relative afferent pupillary defects (RAPDs) in amblyopia have been reported, and it is widely accepted that amblyopes can have an RAPD. We investigated whether or not this could be confirmed by the use of binocular pupillography. We examined twelve patients (6 males and 6 females, aged 7-57 years) with unilateral amblyopia associated with anisometropia and/or strabismus, using binocular infrare...

Foveal vision in strabismic amblyopia can show increased levels of crowding, akin to typical peripheral vision. Target-flanker similarity and visual-acuity test configuration may cause the magnitude of crowding to vary in strabismic amblyopia. We used custom-designed visual acuity tests to investigate crowding in observers with strabismic amblyopia. LogMAR was measured monocularly in both eyes ...

Amblyopes show specific deficits in processing second-order spatial information (e.g. Wong, Levi, & McGraw (2001). Is second-order spatial loss in amblyopia explained by the loss of first-order spatial input? Vision Research, 41, 2951-2960). Recent work suggests there is a significant degree of plasticity in the visual pathway that processes first-order spatial information in adults with amblyo...

To shed light on the basis of normal contrast perception in general and its susceptibility during early visual development in particular the contrast-coding deficit of amblyopic eyes was investigated. This was accomplished by using two different but complementary paradigms, one involving equating the contrast sensations between the amblyopic and normal fellow eye and the other involving the ass...

Stereoscopic depth perception may be obtained from small retinal disparities that can be fused for single vision (fine stereopsis), but reliable depth information is also obtained from larger disparities that produce double vision (coarse stereopsis). Here we assess the possibility that the early development of coarse stereopsis makes it resilient to the factors that cause amblyopia by comparin...