soybean, glycine max, is susceptible to a large number of disease agents such as seedling and root pathogens that cause serious damages to this crop plant. one of these soil-borne pathogens is macrophomina phaseolina, the causal agent of charcoal root rot. in this study, two bacteria, pantoea agglomerans and bacillus sp. bin, and a fungus, trichoderma harzianum t100, as potential biocontrol age...

Verticillium wilt caused by Verticillium spp. results in severe yield losses in a broad range of crops. Verticillium outbreaks are challenging to control, and exacerbated by increases in soil temperatures and drought associated with global warming. Employing natural antagonists as biocontrol agents offers a promising approach to addressing this challenge. Paenibacillus polymyxa Sb3-1 was proven...

In this study, the influence of dopamine receptor agonists and antagonists on antinociception induced by bac10fen has been examined in the formalin test. The GABA-B agonist bac10fen induced antinociception in both phases of the formalin test in mice. The dopamine receptor agonists SKF 38393 and quinpirole also induced antinociception in both phases of the test. SKF 38393 but not quinpirole ...

Losartan potassium, Valsartan , Telmisartan and Irbesartan are angiotensin-II-receptor antagonists (ARA II) group which used in treatment of hypertension alone or in combination with other drugs mainly Hydrochlorothiazide. RP- HPLC method was developed for the assay of three angiotensin-II-receptor antagonists (ARA-IIs) in presence of Hydrochlorothiazide. The method was performed by reversed ph...

In this study the effect of adrenergic receptor agonists and antagonists on physostigmine induced yawning was investigated. Intraperitoneal injection of different doses of physostigmine (0.03, 0.05, 0.1 and 0.2 mg/kg) caused yawning in white rats. The greatest response was seen at a dose of 0.2 mg/kg physostigmine. Phenylephrine, an α1 agonist, and clonidine, an α2 agonist, led to a decrease in...

Background and Purpose New remedies are required for the treatment of neuropathic pain due to insufficient efficacy available therapies. This study provides a novel approach develop painkillers chronic treatment. Experimental Approach The rat formalin test spinal nerve ligation model were used evaluate antinociception protopanaxadiol. Primary cell cultures, immunofluorescence staining, gene pro...

Introduction Olanzapine is a second generation antipsychotic that approved for the treatment of schizophrenia, bipolar disorder type 1 as monotherapy, or an add-on to lithium valproate (manic mixed episodes), and it also used off label acute anxiety, insomnia… It one most effective antipsychotics but concerns remain due its significant metabolic adverse effects. has highest rates weight gain am...

Abstract Background The interest in the development of products that cause less damage to environment associated with loss efficiency chemical nematicides for control management nematodes is growing. Thus, adoption biological or use biopesticides are excellent options these like those based on compounds, such as commercial pesticides and anthelmintic (AH) drugs. Spent mushroom substrate (SMS), ...

Chronic urticaria is highly prevalent in the general population, and while there are multiple treatments for the disorder, the results obtained are not completely satisfactory. The second-generation H1 antihistamines remain the symptomatic treatment option of choice. Depending on the different pharmacokinetics and H1 receptor affinity of each drug substance, different concentrations in skin can...