Dermatomyositis (DM) associated with anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody is a rare autoimmune disease. Anti-MDA5, also known as anti-CADM-140 antibodies. DM affects the skeletal muscle, skin, joints, and lungs form of idiopathic inflammatory myopathy (IIM). All dermatomyositis MDA5+ positive patients had rapidly progressive interstitial lung disease (RP-ILD). cl...

there are many studies related to the production of a elisa kit for diagnosing virus infections. however, production of most kits depends on purification of whole virus particles, which involves the use of costly equipment and reagents. the purpose of this study was to check out if the anti-cp42 antibodies could be used as a diagnostic assay for detection of grapevine fanleaf virus (gflv). in t...

Highly purified human (Lys-forms), cat, dog, and rabbit plasminogens showed significantly different sensitivities to activation by highly purified streptokinase. The most sensitive plasminogen is the human zymogen, followed by the cat, dog, and rabbit zymogens, respectively. These human, cat, dog, and rabbit zymogens reacted with streptokinase to form homogeneous equimolar plasminogen-streptoki...

Fibrinolytic enzymes, particularly streptokinase, are now widely used to treat empyema thoracis. Recent in vitro evidence suggests that streptokinase has no effect on pus viscosity but that deoxyribonuclease (DNase) reduces the viscosity of pus. We report the first use of human recombinant DNase given intrapleurally to treat an empyema which had not resolved after standard treatment with strept...

Abstract Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women infants positive for anti S- anti-receptor binding domain antibody–specific immunoglobulin G. Cord antibody concentrations correlated to maternal levels time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide neonatal protection.

BACKGROUND The nonsurgical medical approach with use of fibrinolytic agent is an alternative modality in management of chronic empyemas. With the introduction of purer forms of streptokinase, there has been renewed interest generated in the use of intrapleural thrombolytics with documented successful drainage of difficult to drain chronic empyemas. To evaluate the utility of streptokinase in th...

Background: There is a controversy about the relation between anti-hepatitis B (anti-HBs) antibody level and obesity. We designed this study to compare the vaccine efficacy in obese/overweight and non-obese cases. Methods: In this cross-sectional study, 242 obese/overweight and 85 non-obese individuals were participated. Cases were selected from a referral clinic for obesity and a referral hepa...

Neospora caninum is an obligate intracellular parasite causing abortion and reproductive failure in ruminants. Here, the seroprevalence of Neospora DNA and anti-Neospora antibodies and the correlation between the DNA and the antibody using polymerase chain reaction (PCR) and a new developed whole cell-based enzyme-linked immunosorbent assay (ELISA) in water buffalo (<...

how to cite this article: allahdin s, khademvatan s, rafiei a, momen aa, rafiei r. frequency of toxoplasma and toxocara sp. antibodies in epileptic patients, in south western iran. iran j child neurol. autumn 2015;9(4):32-40. abstract objective epilepsy is a disorder of the brain characterized by an enduring predisposition to generate seizures. infectious agents are mentioned in its etiology. w...

The therapeutic properties of plasminogen activators are dictated by their mechanism of action. Unlike staphylokinase, a single domain protein, streptokinase, a 3-domain (alpha, beta, and gamma) molecule, nonproteolytically activates human (h)-plasminogen and protects plasmin from inactivation by alpha(2)-antiplasmin. Because a streptokinase-like mechanism was hypothesized to require the strept...