Indonesia is ranked 7th out of 10 countries with the highest number people diabetes mellitus, which estimated to increase every year.α -amylase an enzyme that catalyzes hydrolysis α-1,4 glycosidic bonds polysaccharides produce dextrins, oligosaccharides, maltose and D-glucose. Apis dorsata Binghami honeycomb contains secondary metabolites have antidiabetic potential, including inhibiting action...

In this research work, 2, 4-substituted oxazolone derivatives OXZ-1 to OXZ-5 were screened for antidiabetic activity at 200 and 400 mg/kg b.w. p.o. for 15 days in streptozotocin induced diabetic rats. Acute and sub-acute toxicity studies were performed as per OECD guideline Up and Down Procedure425 and 407. Clinical signs, body weight, hematological, biochemical and histopathological examinatio...

In present study, in vitro α-amylase inhibition and streptozotocin-induced oxidative stress were used to evaluate hypoglycemic effects of Helicteres isora (sterculiaceae). Antidiabetic treatment with of H. isora extract (100 mg/kg and 250 mg/kg body weight) for three weeks showed significant reduction in thiobarbituriuc acid reactive substances (TBRAS) and glutathione reductase (GSH-R) in both ...

Conventional medicine that is being used to treat diabetes exert adverse side effects and therefore scientists have focused on natural hypoglycemic agents. “Sri Wijaya” (CCSW) an accession of Cinnamomum zeylanicum, which shows higher activity. Pressured water extract its dried quills can be as antidiabetic nutraceutical. Higher stability, ease storage transportation, make powder form nutraceuti...

B. pilosa has long been purported to have antidiabetes activity, but despite the advancement in phytochemistry and animal models of diabetes, no human clinical trials have been conducted to date. Here, we evaluated the effect of a B. pilosa formulation on fasting blood glucose (FBG), fasting serum insulin, and glycosylated hemoglobin A1c (HbA1c) in diabetic subjects. The B. pilosa formulation r...

Young edible bamboo shoot (Muia in Kokborok-the third Official Language of Tripura, India) Melocanna baccifera is widely used as a raw food ingredient different dishes Tribal Tripura. Methanolic extract (MEMB) revealed the presence bioactive constituents like alkaloids, fixed oil, flavonoids, triterpinoids, glycosides carbohydrate, protein, and minerals sodium, potassium, calcium, chloride, pho...