There is growing interest in the use of medicinal plants and herbal products for fungal infection related diseases control program because plant derived drugs are considered safe and free from adverse side effects. Plants generally produce many secondary metabolites which constitute an important source of antifungal drugs. Medicinal properties of plants are normally dependent on the presence of...

Background The presence of high levels of aflatoxin is a serious problem to the production of raw peanuts and peanut crumbs. The high incidence of aflatoxin in peanuts in our country is mainly due to problems in primary production. High humidity and temperature conditions increase the likelihood of Aspergillus development and aflatoxins production, which is worsened during rainy weather [1]. Af...

tunistic fungal disease in humans. In fact, this fungus is also known as the fourth leading cause of nosocomial infections. Over the past few decades, increasing incidence of candidiasis due to this fungus parallels the growing numbers of immmunocompromised people. In immunocompromised people, disseminated candidiasis is sometimes a serious disease which often results in death. In addition to t...

BACKGROUND The inappropriate use of antifungals is an important health problem related to increasing adverse effects, unnecessary cost and promotion of resistant and emerging fungal infections. Despite its relevance, many health institutions assign few resources to improve prescribing practices. AIMS To evaluate the efficiency of an antifungal stewardship programme (ASP) centered on restricte...

OBJECTIVES This study aims to systematically identify and summarize the effects of antifungal prophylaxis in non-neutropenic critically ill adult patients on all-cause mortality and the incidence of invasive fungal infections. METHODS Systematic review and meta-analysis of randomized controlled trials in all languages comparing the prophylactic use of any antifungal agent or regimen with plac...

Background: The increasing resistance to antifungal drugs and the reduced number of available drugs led to the search for therapeutic alternatives among aromatic plants and their essential oils, empirically used by antifungal effects. OBJECTIVES: The purpose of the current study was to evaluate the antifungal activity of Trachyspermum ammi essential oil (EO) against the most frequent pathogenic...

Background: Nanoparticles have been applied to medicine, hygiene, pharmacy and dentistry, and will bring significant advances in the prevention, diagnosis, drug delivery and treatment of disease. Green synthesis of metal nanoparticles has a very important role in nanobiotechnology, allowing production of non-toxic and eco-friendly particles.Objectives: Gr...

Dermatophyte fungi are the etiologic agents of skin infections commonly referred to as ringworm. These infections are not dangerous but as a chronic cutaneous infections they may be difficult to treat and can also cause physical discomfort for patients. They are considered important as a public health problem as well. No information is available regarding the efficacy of antifungal agents again...

The potential antifungal effects of Thymus vulgaris L., Thymus tosevii L., Mentha spicata L., and Mentha piperita L. (Labiatae) essential oils and their components against 17 micromycetal food poisoning, plant, animal and human pathogens are presented. The essential oils were obtained by hydrodestillation of dried plant material. Their composition was determined by GC-MS. Identification of indi...

Candida infections (candidiasis) are the most prevalent opportunistic fungal infection on humans and, as such, a major public health problem. In recent decades, candidiasis has been associated to Candida species other than Candida albicans. Moreover, biofilms have been considered the most prevalent growth form of Candida cells and a strong causative agent of the intensification of antifungal re...