common cutaneous disorder with a lifetime incidence between 15% and 25%.1 Urticaria is characterized by recurring pruritic wheals that arise due to allergic and nonallergic reactions to internal and external agents. The name urticaria comes from the Latin word for “nettle,” urtica, derived from the Latin word uro, meaning “to burn.”2 Urticaria can be debilitating for patients, who may complain ...

Pruritus is a common complaint associated with many conditions. It negatively impacts sleep, quality of life, and mortality. Itch is transmitted along both histaminergic and non-histaminergic pathways with a complex interplay between keratinocytes, immune cells and cutaneous neurons. Individuals who present with pruritus should undergo a thorough assessment, especially those over 65 years old, ...

It's a great idea that you're looking into whether certain substances may have the potential for problematic or undesirable results! To answer your question ? it?s best to avoid mixing alcohol and antihistamines, as they both depress the central nervous system (CNS) [2], thereby impairing your ability to coordinate physical motor movements and remain awake and conscious. Additionally, alcohol d...

It's a great idea that you're looking into whether certain substances may have the potential for problematic or undesirable results! To answer your question ? it?s best to avoid mixing alcohol and antihistamines, as they both depress the central nervous system (CNS) [2], thereby impairing your ability to coordinate physical motor movements and remain awake and conscious. Additionally, alcohol d...

Anti-histamines represent the mainstay of the treatment of allergic rhinitis and urticaria (1-2). However, as in every chronic condition, adherence to the therapy is relevant and a regular long-term use is more effective than an use on demand in both these conditions (3). The present survey investigated doctors’ opinions about the use of antihistamines, and looked for criticisms and unmet needs...

A case of toxic psychosis due to antihistamine poisoning is described. The reversal of this state by physostigmine supports the contention that it is caused by an anticholinergic syndrome. The management of antihistamine poisoning is discussed.

Histamine is an important mediator of asthma. The new anti-histamines which block histamine at the H1-receptor level also possess some anti-allergic properties. At current dosages they appear to be safe. These drugs are effective in the treatment of rhinitis and conjunctivitis but their role in asthma is still under investigation. At a dose higher than usually recommended, they were shown to bl...

BACKGROUND Chronic idiopathic urticaria (CIU) is a common cutaneous disorder but the influence of initial treatment modality on long-term control is not known. The aim of this study was to evaluate clinical features, and the influence of initial treatment modality on long-term control. METHODS AND RESULTS 641 CIU patients were enrolled from the allergy clinic in a tertiary referral hospital. ...