Plasmodium vivax merozoite surface protein 1 (PvMSP-1) has been considered a major candidate for the development of an antimalaria vaccine, but the molecule exhibits antigenic diversity among isolates. The extent of genetic polymorphism in the region between interspecies conserved blocks 4 and 5 (ICB4 and ICB5) of the PvMSP-1 gene was analyzed for 30 Korean isolates. Two genotypes, SK-A and SK-...

rural women in pakistan, under a small holding system of farming, play a pivotal role in farming. they actively participate in a range of activities related to crop production and livestock management. rural women remain busy from dawn to dusk in various agricultural activities, including pre-harvest, post-harvest and livestock management. their participation is well dispersed but less perceive...

background: the recently reported resistance to antimalarials contributes to making the control of ma­laria more difficult. there is a need to evaluate the current antimalaria regimens to prevent this emerging problem. the aim of this study was to determine dihydrofolate reductase-thymidylate synthase gene mu­tation ( pvdhfr ) regarding antifulate resistance in plasmodium vivax . methods : from...

key international organizations and businesses—set a timetable for comprehensive malaria control in Africa by the end of 2010. Secretary-General Ban has thrown down the gauntlet: there is no reason why a million or more children should die every year of a largely preventable and wholly treatable disease. The operational objective is to ensure that crucial interventions are taken continent-wide ...

Malaria is a protozoal disease transmitted by the Anopheles mosquito, caused by minute parasitic protozoa of the genus Plasmodium, which infect human and insect hosts alternatively. It affects over 40% of the worldís population, with 120 million cases reported, and about 2 million deaths annually (1). The P. falciparum variety of the parasite accounts for 80% of cases and 90% of deaths caused b...

Despite declining the number of malaria cases in Iran, increased prevalence of malaria is supposed to be due to migration from eastern neighboring countries of Iran, which are abundant in Plasmodium vivax (P. vivax). The circumsporozoite protein (CSP) of the P. vivax, is one of the candidate antigens for antimalaria vaccine. The diversity of P. vivax populations circulating in Iran has been inv...

BACKGROUND & OBJECTIVES The distribution of insecticide-treated bednets (ITNs), as an alternative to untreated bednets or no bednet at all, not only directly prevents the mosquito from biting an individual, but kills the mosquito as well. This reduces the mosquito infestation at the household and community levels. However, barriers may exist limiting the effectiveness of malaria prevention by t...