This paper addresses clinical controversies and uncertainties regarding thoracic aortic aneurysm and its treatment. 1) Estimating true aortic size is confounded by obliquity, asymmetry, and noncorresponding sites: both echocardiography and computed tomography/magnetic resonance imaging are necessary for complete assessment. 2) Epidemiology of thoracic aortic aneurysm. There has been a bona fide...

BACKGROUND Carriers of the 719Arg variant in KIF6, compared with noncarriers, have been reported to be at greater risk for coronary heart disease (CHD) in six prospective studies. Because CHD, thoracic aortic dissection, and nondissection thoracic aortic aneurysm share some risk factors and aspects of pathophysiology, we investigated whether carriers of the 719Arg variant also have greater odds...

Purpose: Non-respective treatment of the abdominal aortic aneurysm by proximal and distal ligation of the aneurysm sac (exclusion) combined with aortic bypass known as Debakey Procedure has been previously reported. A 2 year experience with 10 patients undergoing this procedure was reviewed. Methods: From 2010 to 2012, 10 patients of abdominal aortic aneurysm underwent repair with the retroperi...

Intraluminal thrombus is a consistent feature of human abdominal aortic aneurysm (AAA). Coagulation factor Xa (FXa) catalyses FII to thrombin (FIIa). We examined the effect of FXa/FIIa inhibition on experimental aortic aneurysm in apolipoprotein E-deficient (ApoE-/-) mice infused with angiotensin II (AngII). The concentration of FXa within the supra-renal aorta (SRA) correlated positively with ...

OBJECTIVE The aim of the study was to determine the risk factors for descending aortic aneurysmal changes following surgery for acute DeBakey type I aortic dissection. METHODS A total of 129 patients who underwent surgery for acute type I aortic dissection between 2000 and 2010 were evaluated by contrast-enhanced computed tomography (CT) at least 6 months later (median follow-up 29.5 months, ...

AIM To investigate the diagnostic value of ischemia-modified albumin (IMA) in the diagnosis oflpatients with aortic aneurysm. MATERIALS AND METHODS The study group consisted of 98 patients who presented to our university hospital emergency department with aortic pathology and were definitively diagnosed using spiral tomography. The control group consisted of 101 healthy individuals with simil...

Since 1991 ten patients, 9 male and 1 female, with aortic arch aneurysm underwent surgical therapy with trapdoor thoracotomy. The mean age was 67.4 +/- 9.1 (standard deviation) years at operation. In addition to the aortic arch repair, we also performed seven descending aortic replacements. We performed one partial arch replacement, one total arch replacement, and one aneurysmorrhaphy and wrapp...

primary non-hodgkin lymphoma of the larynx is rare, accounting for less than 1% of all laryngeal neoplasms. fewer than 100 cases have been reported in the literatureand to our knowledge this may be the first reported case of laryngeal non hodgkin lymphoma presented with hoarseness, aortic aneurysm, hepatitis b and skin rashes.

I t is not unusual for complicated aneurysms of the ascending aorta to affect left ventricular function. Processes causing or associated with an aneurysm may narrow the coronary artery ostia and produce myocardial ischemia or infarction; the aneurysm may distort the aortic valve ring and produce aortic insufficiency with subsequent left ventricular hypertrophy, dilatation, and failure. However,...

Thoracic aortic aneurysm is often an asymptomatic but potentially lethal disease if its most catastrophic complication - aortic dissection - occurs. Thoracic aortic dissection is associated with a high mortality rate despite ongoing improvement in its management. We report a fatal outcome of thoracic aortic aneurysm in a male patient with bicuspid aortic valve. The patient was qualified for ele...