OBJECTIVE To evaluate the effectiveness of the topical corticosteroids compared to a placebo in shortening the clinical course and recurrence of aphthous stomatitis. MATERIALS AND METHOD The inclusion criteria and the literature review databases were defined using MEDLINE, Lilacs, SciELO, and EMBASE. The quality of the studies was evaluated using the Jadad scale. The data were then extracted ...

Recurrent aphthous stomatitis (canker sores) is a very common oral condition that remains incompletely understood. Presentation has been well-classified into minor, major or herpetiform subcategories based on clinical features, but exact etiology is unknown. Because etiology is unclear, treatments are primarily empiric and aimed at symptom reduction rather than prevention or cure. However, ther...

OBJECTIVES To assess the levels of procalcitonin (PCT) and C-reactive protein (CRP) in children diagnosed with PFAPA (periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis) during their febrile attacks. METHODS 23 patients with diagnosis of PFAPA included into the study prospectively during a three years period. In these patients, CRP and PCT values were recorded during 78 f...

OBJECTIVE The aim of this study was to detect the prevalence of oral H.pylori among adults and to investigate the correlation between H.pylori infection and common oral diseases. STUDY DESIGN A cross-sectional study was performed among adults Chinese who took their annual oral healthy examination at The First Affiliated Hospital, Zhejiang University School of Medicine, China. RESULTS The st...

Introduction Periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome is an autoinflammatory disorder of childhood and little is known about the underlying etiology, pathogenesis or the reason behind the success of tonsillectomy. Numerous immune cell types are present in the tonsillar microenvironment, each of which may contribute to the pattern of symptoms observed in PFA...

BACKGROUND Amlexanox has been developed as a 5 percent topical oral paste for the treatment of patients with recurrent aphthous stomatitis (RAS) in most European countries. However, it is not yet available in China and has not been generally accepted in clinical treatment. The aim of this study was to explore the effectiveness of amlexanox oral adhesive pellicles in the treatment of minor recur...

radical mastectomy in 2000 for an invasive ductal carcinoma of the right breast without lymph node metastasis. Although the patient subsequently received adjuvant chemotherapy, she developed a solitary minute gastric metastasis, which was removed by endoscopic resection [1]. She was treated by chemotherapy for the following 6 months. Thereafter, the clinical follow-up showed no signs of tumor r...

BACKGROUND Recurrent aphthous stomatitis (RAS) is the most common painful ulcers of oral mucosal which can cause many sufferings. Treatment of RAS often includes administration of corticosteroids, analgesics and regulators of the immune system. However, considering the side effects of these medications, even their topical application must be done with caution. Alum is used in traditional medici...