Flavonoids are polyphenolic compounds that are ubiquitous in plants and have biological effects on cancer cells and other cell types. In particular, apigenin (API) has been shown to bind to estrogen receptors, which affect the development, maturation, function, and plasticity of the nervous system. The aim of this study was to investigate the effects of 4?,5,7trihydroxyflavone (API) upon the ne...

BACKGROUND Characterization of IgE-binding epitopes of allergens and determination of their patient-specific relevance is crucial for the diagnosis and treatment of allergy. OBJECTIVE We sought to assess the contribution of specific surface areas of the major birch pollen allergen Bet v 1.0101 to binding IgE of individual patients. METHODS Four distinct areas of Bet v 1 representing in tota...

Aminopeptidase I (API) is a soluble leucine aminopeptidase resident in the yeast vacuole (Frey, J., and K.H. Rohm. 1978. Biochim. Biophys. Acta. 527:31-41). The precursor form of API contains an amino-terminal 45-amino acid propeptide, which is removed by proteinase B (PrB) upon entry into the vacuole. The propeptide of API lacks a consensus signal sequence and it has been demonstrated that vac...

With the growing size of Application Programming Interfaces (APIs), both API usability and API learning become more challenging. API learning resources are often crucial for helping developers learn an API, but they are distributed across different documents, which makes finding the necessary information more challenging. This work focuses on discovering relevant sections of tutorials for a giv...

This paper presents a work inspired by the Pachycondyla apicalis ants behavior for the clustering problem. These ants have a simple but efficient prey search strategy: when they capture their prey, they return straight to their nest, drop off the prey and systematically return back to their original position. This behavior has already been applied to optimization, as the API meta-heuristic. API...

Web APIs provide a systematic and extensible approach for application-to-application interaction. A large number of mobile applications makes use of web APIs to integrate services into apps. Each Web API’s evolution pace is determined by their respective developer and mobile application developers are forced to accompany the API providers in their software evolution tasks. In this paper we inve...

background : cockroaches mechanically spread pathogenic agents, however, little is known about their gut microbiota. identification of midgut microbial community helps targeting novel biological control strategies such as paratransgenesis. here the bacterial microbiota of periplaneta americana midgut, were identified and evaluated for finding proper paratransgenesis candidate. methods : midgut ...

OBJECTIVE This study examined subsite-specific colorectal cancer incidence rates and stage distributions for Asians and Pacific Islanders (API) and compared the API data with data for Whites and African Americans. METHODS Data included 336,798 invasive colorectal cancer incident cases for 1995 to 1999 from 23 population-based central cancer registries, representing about two thirds of API pop...