نتایج جستجو برای: approval of indications
تعداد نتایج: 21167475 فیلتر نتایج به سال:
Drugs with similar side-effect profiles may share similar therapeutic properties through related mechanisms of action. In this study, a drug-drug network was constructed based on the similarities between their clinical side effects. The indications of a drug may be inferred by the enriched FDA-approved functions of its neighbouring drugs in the network. We systematically screened new indication...
LEARNING OBJECTIVES After studying this article, the participant should be able to: 1. Describe the alternatives for auricular reconstruction. 2. Discuss the pros and cons of autogenous reconstruction of total or subtotal auricular defects. 3. Enumerate the indications for prosthetic reconstruction of total or subtotal auricular defects. 4. Understand the complexity of and the expertise require...
Several multi-winner systems that use approval voting have been developed but they each suffer from various problems. Six of these methods are discussed in this paper. They are Satisfaction Approval Voting, Minimax Approval Voting, Proportional Approval Voting, Monroe's Fully Proportional Representation, Chamberlin-Courant's Rule, and Ebert's method. They all fail at least one of Proportional R...
OBJECTIVE To determine the impact of the introduction of new pre-written orders for antimicrobials in a computerized provider order entry (CPOE) system on 1) accuracy of documented indications for antimicrobials in the CPOE system, 2) appropriateness of antimicrobial prescribing, and 3) compliance with the hospital's antimicrobial policy. Prescriber opinions of the new decision support were als...
We examine the impact of a desire for social approval on education and occupation choice and model the endogenous determination of perceptions that influence such approval. In a two-sector overlapping generations framework, agents born with ability endowments in both occupations must choose one as their career. An agent’s choice is influenced by social approval, which depends upon the community...
The first kinase inhibitor drug approval in 2001 initiated a remarkable decade of tyrosine kinase inhibitor drugs for oncology indications, but a void exists for serine/threonine protein kinase inhibitor drugs and central nervous system indications. Stress kinases are of special interest in neurological and neuropsychiatric disorders due to their involvement in synaptic dysfunction and complex ...
urolithiasis has become a worldwide problem with the prevalence of the disease increasing over the past few decades. while various treatment modalities have evolved over the years, discrepancies exist regarding the clinical indications and the efficacy of each of these treatment options. in the present review, we aim to review the current treatment modalities for urinary tract stones to provide...
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