OBJECTIVES The aim of this study was to determine the prevalence of liver fibrosis in patients with human immunodeficiency virus (HIV) monoinfection versus those with HIV hepatitis-B virus (HBV) co-infection as assessed with shear wave elastography (SWE) in a tertiary sub-Saharan Africa hospital. MATERIALS AND METHODS A total of 105 consecutive patients, 70 with HIV monoinfection and 35 with ...

Amaç: Tuboovaryan apse (TAO) olgularında sistemik inflamatuar belirteçler ve Aspartate aminotransferaz/Platelet Index (APRİ) skorun medikal tedavi başarısızlığını öngörmede yeri olup olmadığı araştırıldı. Gereç Yöntem: Ağustos 2016 – Ekim 2020 tarihleri arasında TOA tanısı ile yatırılarak edilen 240 hasta çalışmaya dâhil edildi. Hastaların demografik klinik özellikleri, tanı anında bakılan C- R...

Highlights: 1. The Child-Pugh score is an instrument to assess the degree of severity and prognosis chronic liver disease. 2. rise in APRI may predict advance cirrhosis stages. Abstract: Background: Simple diagnostic screening methods are needed assist with biopsy, which not always available local health facilities. Objective: To AST-to-Platelet Count Index (APRI) as a means stages indicated cl...

Methods: Treatment naive CHC patients were enrolled. They were classified into 2 groups according to presence or absence of PHT. Patients were subjected to liver function tests (LFTs), hepatitis C virus antibody (HCV-Ab), hepatitis B surface antigen (HBs-Ag), anti-nuclear antibody (ANA), Bilharzial agglutination titer, ultrasound abdomen and oesophago-gastro-duodensocpy. Egy-Score, ASTto-Platel...

BACKGROUND Several noninvasive predictive models were developed to substitute liver biopsy for fibrosis assessment. AIM To evaluate the diagnostic value of fibronectin which reflect extracellular matrix metabolism and standard liver functions tests which reflect alterations in hepatic functions. MATERIAL AND METHODS Chronic hepatitis C (CHC) patients (n = 145) were evaluated using ROC curve...

 Background and rationale. Nonalcoholic fatty liver disease (NAFLD) is the most common cause of pediatric liver disease in western countries. Its prevalence in Indian subcontinent is not well studied. MATERIAL AND METHODS In a school based cross sectional study we have screened overweight and obese children in the age group of 11 to 15 years for NAFLD. Ultrasonography, elevated serum transami...

Fucosylated haptoglobin (Fuc-Hpt) and Mac-2 binding protein (Mac-2 bp) are identified as cancer biomarkers, based on the results from a glyco-proteomic analysis. Recently, we reported that these glyco-biomarkers were associated with liver fibrosis and/or ballooning hepatocytes in patients with nonalcoholic fatty liver disease (NAFLD). We evaluated the ability of these glycoproteins to estimate ...

BACKGROUND Finding a noninvasive method to predict liver fibrosis using inexpensive and easy-to-use markers is important. OBJECTIVES We aimed to clarify whether NX-des-γ-carboxyprothrombin (NX-DCP) could become a new noninvasive model to predict liver fibrosis in hepatitis C virus (HCV) related liver disease. PATIENTS AND METHODS We performed a prospective cohort study on a consecutive grou...

BACKGROUND Hepatitis C virus is a worldwide problem. Noninvasive methods for liver fibrosis assessment as ultrasound-based approaches have emerged to replace liver biopsy. The aim of this study was to evaluate the diagnostic accuracy of real-time elastography (RTE) in the assessment of liver fibrosis in patients with chronic hepatitis C (CHC), compared with transient elastography and liver biop...