The statistical methodology for the design and analysis of clinical Phase II dose-response studies, with related software implementation, is well developed for the case of a normally distributed, homoscedastic response considered for a single timepoint in parallel group study designs. In practice, however, binary, count, or time-to-event endpoints are encountered, typically measured repeatedly ...

introduction: the framework convention tobacco control (fctc) is designed by world health organization (who), in response to the globalization of the tobacco epidemic, in 2003. all treaty signatories including iran adopted to perform it during 3 years. this study was performed to design a model for evaluation of the implementation of this treaty in iran. methods: this study was a qualitative st...

The motivation for this work is to propose a first thorough review of dough rheological models used in numerical applications. Although many models have been developed to describe dough rheological characteristics, few of them are employed by researchers in numerical applications. This article reviews them in detail and attempts to provide new insight into the use of dough rheological models.

background: in modern life, the incidence of traumatic injuries increases daily. in accidents which lead to trauma, massive bleeding is the main cause of death. nowadays, many different chemical and herbal agents are available for quick control of bleeding. objectives: in this study, we compare the effectiveness of two different types of chemical agents for control of bleeding in an animal mode...

BACKGROUND Considerably little is known about the biological role and clinical significance of androgen receptor expression in breast cancer. The objectives of this study were to characterize AR-CAG repeat genotypes in a cohort of women with breast cancer and to determine the influence of AR on response to neoadjuvant chemotherapy and clinical outcome. MATERIALS AND METHODS Genotyping of the ...

0022±2836/98/380495±10 $30.00/0 The lac operon of Escherichia coli is positively regulated by the catabolite activator protein (CAP) bound upstream of the ÿ45 region (CAP binding is centered at ÿ61.5; the ÿ45 region extends from ÿ50 to ÿ38). Certain mutations within the ÿ45 region generate sequences that resemble UP elements in base composition and mimic the stimulation by the rrnBP1 UP element...

We developed a new semi-supervised EM-like algorithm that is given the set of objects present in eachtraining image, but does not know which regions correspond to which objects. We have tested thealgorithm on a dataset of 860 hand-labeled color images using only color and texture features, and theresults show that our EM variant is able to break the symmetry in the initial solution. We compared...

Treatment of common pathogens, such as Salmonella species, Escherichia coli, Staphylococcus aureus, etc., is a big challenge for practitioner. Antibiotics’ side effects during their application the treatment infectious diseases should not be underestimated they have many issues, transfer antibiotics-resistant genes, dysbiosis, and antibiotic-resistant strains, which main hurdle in eradication d...

the main objective of this article is to present a comparative study of capital assets pricing models (capm) with extrapolating capital assets pricing models (x-capm) of companies admitted in tehran exchange market which is accomplished for the first time by investigators of this research in iran. accordingly, the statistical population under study of this research includes all companies admitt...

this paper is a translation of a chapter of the hook written by jonathan e. ingersoll jr. the farsi translation will he of great help to iranian students studying option pricing models.