Introduction: Ischaemic or arterial ulcer occurs when there is an obstruction in the supply to a particular part of human body leading necrosis. These are extremely painful types chronic wounds. Treating ulcers difficult task for physician since supportive measures such as compression therapy and leg elevation contraindicated. Surgical intervention ultimate approach manage conventional medicine...

Obstructive sleep apnea (OSA) is the most common respiratory disturbance of sleep and is closely associated to cardiovascular diseases. In humans, apnea increases respiratory effort and elevates muscle sympathetic nerve activity (SNA), but the primary stimulus for the SNA activation has not been identified. We recently developed a model of apnea in rodents using acute airway obstruction. In thi...

Aim . To study the levels of pro-inflammatory biomarkers in patients with obstructive and non-obstructive coronary artery disease (CAD), to identify possible differences for diagnosing degree obstruction. Material methods The observational included two groups patients: (main group, stenosis <50%; n=30) (comparison hemodynamically significant according results angiography; CAD. interleukin-1β...

Abstract The feline hypertrophic cardiomyopathy (HCM) is one of many cardiac diseases known in domestic animals, and it especially frequent cats all ages. HCM the most common heart disease cats, affecting almost 15 % population. Maine Coon Ragdoll breeds are shown to have a special gene that responsible for appearance these breeds. Hypertrophic can be detected by: echocardiography, electrocardi...

The role of thromboxane (TP) in the vasoconstriction induced by tubuloglomerular feedback or 18-h ureteral obstruction was studied in wild type mice (TP +/+), and in heterozygous (TP +/-) and homozygous TP receptor knockout mice (TPR -/-). TGF function was assessed from the response of stop flow pressure (PSF) to a maximum increase in loop of Henle flow rate (0-30 nL min-1). PSF fell by 6.4 +/-...

The concentration of carboxyhaemoglobin (COHb) is often estimated from measurements of carbon monoxide in the exhaled air (COexh). This study investigates whether the presence of airflow obstruction significantly alters the relationship between COexh and COHb. Eighty-one regular smokers were prospectively studied and divided in four groups according to the presence and severity of airflow obstr...

IT IS NOW well appreciated that following a successful valvulotomy for valvular pulmonic stenosis, muscular hypertrophy in the right ventricular outflow tract may persist and be responsible for a significant resistance to right ventricular ejection.'-3 Similar muscular obstruction to the left ventricular outflow has also been noted in patients following surgical relief of discrete valvular or s...

To test the feasibility of imaging the left main coronary artery (LMCA) noninvasively as a means of detecting left main coronary artery disease, we studied 73 patients who underwent cardiac catheterization and cross-sectional echocardiography. Fifty-two had a normal LMCA (controls) and 21 had significant obstruction (greater than or equal to 50% luminal reduction). The apical, tomographic, cros...

BACKGROUND Recent studies find that a considerable number of patients with pulmonary arterial hypertension (PAH) develop fibrous obstruction of the pulmonary veins. Such obstruction more commonly accompanies connective tissue disorder (CTD)-associated PAH than idiopathic PAH. However, few researchers have gauged the risk of death involving obstruction of the pulmonary veins. METHODS Thirty-se...