Natural immune system is a complex of cells, tissues and organs that work together to protect the host against foreign invaders' attacks. Immune network theory proposed by Jerne indicates that the immune system, even in the absence of foreign stimuli, must display an eigen-behavior resulting from cell-cell interactions within the immune system. In this paper, motivated by the natural immune pri...

In this study a device for automatic electrochemical analysis was designed. A three electrodes detection system was attached to a positioning device, which enabled us to move the electrode system from one well to another of a microtitre plate. Disposable carbon tip electrodes were used for Cd(II), Cu(II) and Pb(II) ion quantification, while Zn(II) did not give signal in this electrode configura...

The sub-symbolical representation often corresponds to a pattern that mirrors the way the biological sense organs describe the world. Sparse binary vectors can describe sub-symbolic representation, which can be efficiently stored in associative memories. According to the production system theory, we can define a geometrically based problemsolving model as a production system operating on sub-sy...

It has been well documented that shear forces effective above a certain magnitude under flow conditions causes damage in blood cells. This damage ranges from slight morphological alteration to the destruction of red blood cells (RBC). The hemolytic trauma to RBC can easily be detected by measuring free hemoglobin level in plasma, however there are no standardized protocols to quantitate subhemo...

Bioartificial livers have yet to gain clinical acceptance. In a previous study, a theoretical model was utilized to create operating region charts that graphically illustrated viable bioartificial liver configurations. On this basis a rationale for the choice of operating and design parameters for the device was created. The concept is extended here to include aspects of liver zonation for furt...

Porcine hepatocytes are considered the cell type of choice for bioartificial liver and cell transplantation techniques in support of patients with liver failure. A protocol for cryopreservation of hepatocytes that function adequately after thawing would allow on-demand usage and long-term storage. We conducted experiments to evaluate the freeze rate, concentration of hepatocytes during storage,...

However we can distinguish three basic recommendation approaches: demographic, contentbased and collaborative [7], they are using many different general reasoning methods know from many other disciplines such as Artificial Intelligence, Expert Systems or Information Retrieval. Recently, the recommender systems also adopt some nature inspired methods such as artificial immune system [4,7]. In th...