Australia was the world’s highest per capita consumer of asbestos in the previous century. As such, it is considered to be a sentinel site for observing, over time, the deleterious human health, environmental, economic and social effects associated with high levels asbestos exposure.1 The increasing awareness of the dangers of asbestos among asbestos workers in Australia and the public request ...

Asbestos-exposure is associated with an increased risk of lung cancer, one of the leading causes of cancer deaths worldwide. Asbestos is known to induce DNA and chromosomal damage as well as aberrations in signalling pathways, such as the MAPK and NF-kappaB cascades, crucial for cellular homeostasis. The alterations result from both indirect effects through e.g. reactive oxygen/nitrogen species...

A prospective cohort study of 3,893 shipyard workers, mainly exposed to chrysotile, indicated no increased risk of lung cancer 7-15 yrs after exposure to asbestos had ceased. The shipyard workers, however, had an increased risk of pleural mesotheliomas with 11 observed cases versus 1.5 expected. An explanation for these observations may be that asbestos may have different carcinogenic mechanism...

Despite the fact that asbestos is a known carcinogen to humans, it is still used in industrialized countries, especially Asian countries. The global incidence of asbestos-related diseases (ARDs) due to the past use of asbestos, continues to increase, although many countries have adopted a total ban on asbestos use. The implementation of effective strategies to eliminate ARDs is therefore an imp...

OBJECTIVES To review evidence about the joint relation of exposure to asbestos and smoking on the risk of lung cancer to answer three questions: (1) does asbestos increase risk in non-smokers; (2) are the data consistent with an additive model; and (3) are the data consistent with a multiplicative model? METHODS Analysis of 23 studies reporting epidemiological evidence on the joint relation. ...

Asbestos is a known carcinogen and exposure can lead to lung cancer and malignant mesothelioma. To examine the effects of asbestos fibers on human immune cells, the human T cell leukemia/lymphoma virus (HTLV)-1 immortalized human T cell line MT-2 was employed. Following continuous exposure to asbestos fibers for more than eight months, MT-2 sublines showed acquisition of resistance to asbestos-...

Asbestos is characterised by a unique set of physical and chemical properties, which has led to its many applications [28], such as roofing coatings: flat and corrugated sheets, floors, water supply pipes, textiles, rope, cord and yarn, paper, friction and composition materials, household products, plastic fillers, clutches, brake linings, gaskets and pads for automobiles [30]. Asbestos‐cement ...

Background: there is no resolutive treatment for asbestos-related diseases, but prevention plays a key role. This survey was conducted to test the feasibility of questionnaire measure awareness on asbestos among students in specific polluted area. Furthermore, we carried out preliminary assessment student this topic. Methods: used secondary school Casale Monferrato. considered levels sensitivit...

In Italy, use and production of asbestos asbestos-containing materials (ACMs) were banned in 1992, however, the risk exposure to still exists, because most ACMs are located industrial public buildings. A total 111 Italian buildings with friable non-friable surveyed; 500 air samples collected areas where contamination might have occurred. Airborne fiber concentration calculated from was averaged...