Multicentric Castleman's disease (MCD) is a polyclonal lymphoproliferative disorder that manifests as marked hyper-γ-globulinemia, severe inflammation, anemia, and thrombocytosis. Recently, Takai et al. reported a new disease concept, TAFRO syndrome, named from thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly. Furthermore, Kojima et al. reported Japanese MCD cases with ef...

Glomeruloid hemangioma is characterized by coiled capillary vessels contained within enlarged vascular spaces displaying an architecture that resembles renal glomeruli. The condition is strongly associated with POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy and Skin changes). The present paper reports on two cases of glomeruloid hemangiomas associated with P...

The present case showed M protein spike with varying type of plasma dyscarasias, ascites, gynaecomastia, impotence and mild acanthosis. POEMS syndrome is a rare multisystem disorder involving polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes. It usually manifests in 5–6 decade of life with a mean survival period of 8 years. We report a case of a 56 years old m...

Patients with cirrhosis who develop tense ascites and hepatorenal syndrome have a very high mortality and present a management challenge. Current debate stems from a lack of studies evaluating changes in effective arterial blood volume following paracentesis or targeting fluid replacement with appropriate vascular physiological measures to ensure no paracentesis-related circulatory dysfunction....

Glomeruloid hemangioma is characterized by coiled capillary vessels contained within enlarged vascular spaces displaying an architecture that resembles renal glomeruli. The condition is strongly associated with POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy and Skin changes). The present paper reports on two cases of glomeruloid hemangiomas associated with P...

Hepatorenal syndrome is a life-threatening complication occurring commonly in cirrhosis liver and rarely in acute liver failure. It can be precipitated by shock, infection, surgery, large volume paracentesis or nephrotoxic drugs. Type I hepatorenal syndrome which usually develops over acute liver failure is rapidly progressive and has poor outcome. Type II hepatorenal syndrome is usually associ...

The Budd-Chiari syndrome is a heterogeneous group of disorders characterized by obstruction of hepatic venous outflow at any level from the small hepatic veins to the junction of the inferior vena cava with the right atrium. We present two cases of Budd- Chiari syndrome with severe ascites associated with polycythemia vera in first case and protein C deficiency in the second, in both cases tran...

BACKGROUND Cardiac and pulmonary complications can occur in patients with advanced liver disease. CASE PRESENTATION A woman her fifties diagnosed non-alcoholic steatohepatitis (NASH), which progressed four years later to decompensated failure due cirrhosis. She was admitted the hospital ascites pleural effusion more than 10 times over course of one year, accepted for transplantation. After spen...

Renal failure is common in cirrhosis, especially in patients with ascites. It is typically secondary to one or more intercurrent events, which further compromise renal perfusion on a background of a relative reduction in renal perfusion and may have a negative impact on survival. An accurate and prompt diagnosis and treatment of renal complications in cirrhosis is therefore essential to improve...

Tyrosinemia is a rare metabolic disease resulting from disorder of amino acids, which can occur under the «masks» various diseases, debut as hemorrhagic syndrome in children all age groups, hepatolienal syndrome, hypoglycemia, rickets-like disease, peripheral neuropathy. Clinical case. In our publication, we report on girl at 1 year 7 months who had recurrent nosebleeds, led to referral hematol...