Cancer cells require nutrients and energy to adapt to increased biosynthetic activity and depend on mitochondrial oxidative phosphorylation (OXPHOS) and glycolysis. Whereas they exhibit a pronounced Warburg effect, their TCA cycle remains intact and becomes more dependent on glutamine metabolism through glutaminolysis[1]. Besides this role, intracellular glutamine is also essential for mTORC1 a...

An extraction technique is described for vitamin K1 in medical foods, using accelerated solvent extraction (ASE) in conjunction with matrix solid-phase dispersion (MSPD). The medical food sample is treated as it would be with MSPD extraction, followed by ASE for a hands-free automated extraction. The vitamin K1 in the ASE extract is then quantitated by reversed-phase liquid chromatography with ...

All-to-all broadcast is to disseminate a unique message from each node to every other node of the network. This paper investigates the impact of some of the physical layer impairments on the optical all-to-all broadcast in linear array, bidirectional ring and hypercube networks. The physical layer impairments include Amplified Spontaneous Emission (ASE) noise, switch induced crosstalk and demux...

In this paper, we consider a novel cache-enabled heterogeneous network (HetNet), where macro base stations (BSs) with traditional sub-6 GHz are overlaid by dense millimeter wave (mmWave) pico BSs. These two-tier BSs, which are modeled as two independent homogeneous Poisson Point Processes, cache multimedia contents following the popularity rank. High-capacity backhauls are utilized between macr...

Cardiovascular disease is a major cause of death worldwide, so people are advised to limit their intake of dietary cholesterol [1]. Egg consumption has been seriously reduced because of the high levels of cholesterol [2]. The objective of this study was to evaluate the cholesterol metabolism effects of alfalfa saponin extract (ASE) in liver and ovary tissues using digital gene-expression (DGE) ...

We demonstrated a simple, directly-readable approach for high resolution pH sensing. The method was based on sharp changes in Amplified Spontaneous Emission (ASE) of a Stilbene 420 (ST) laser dye triggered by the pH-dependent absorption of Bromocresol Green (BG). The ASE threshold of BG:ST solution mixtures exhibited a strong dependence on BG absorption, which was drastically changed by the var...

Amplified spontaneous emission (ASE) is a process which competes with laser-induced fluorescence (LIF) in three level systems. This was demonstrated in the case of oxygen atoms, for which both ASE and LIF were observed at 845 nm. Ground state oxygen atoms were generated by photodissociating 02, SOa, and NO2 in a pump and probe experiment. Both nascent and thermalized O(3P,+p) atoms were measure...

To investigate the influence of maternal Se supply and plane of nutrition on lamb morbidity, mortality, and passive transfer of IgG, pregnant ewe lambs were used in 2 experiments with 2 × 3 factorial treatment arrangements. Supplementation of Se began at breeding and was either adequate Se (ASe, 9.5 μg/kg of BW) or high Se (HSe, 81.8 μg/kg of BW) in Exp. 1 or ASe (11.5 µg/kg of BW) or HSe (77.0...

Roberto M. Lang, MD, FASE*‡, Luigi P. Badano, MD, FESC†‡, Wendy Tsang, MD*, David H. Adams, MD*, Eustachio Agricola, MD†, Thomas Buck, MD, FESC†, Francesco F. Faletra, MD†, Andreas Franke, MD, FESC†, Judy Hung, MD, FASE*, Leopoldo Pérez de Isla, MD, PhD, FESC†, Otto Kamp, MD, PhD, FESC†, Jaroslaw D. Kasprzak, MD, FESC†, Patrizio Lancellotti, MD, PhD, FESC†, Thomas H. Marwick, MBBS, PhD*, Marti ...

Background and Aim: Seeds from Carica pubescens were observed to be abundant as waste. This waste contains active plant compounds whose utilization has not been studied in the livestock sector. study was conducted evaluate potential of an aqueous seed extract (ASE) anthelmintic agent during rumen fermentation methane reduction. Materials Methods: Aqueous prepared C. cultivated Wonosobo, Indones...