A quartz crystal microbalance was used for real-time monitoring of fibrinogen cross-linking on three model biomaterial surfaces. Fibrinogen adsorbs slowly and forms a less rigid multi-layer on hydrophobic surfaces, while it adsorbs quickly, forming a single mono-layer on hydrophilic surfaces. The extent of fibrinogen cross-linking is greater on hydrophobic surfaces. Fibrinogen cross-linking can...

The procedure for the combinatorial fabrication of new sensing materials for cations and anions based on self-assembled monolayers (SAM) is discussed. A library of different sensitive substrates is generated by sequential deposition of fluorophores and small ligand molecules onto an amino-terminated SAM coated glass. The preorganization provided by the surface avoids the need for complex recept...

• The CM(covariation model) files built and calibrated from the curated alignments above are in folder CM files. For each family, the cm files for all alternative structures are included. However, the pseudoknotted hairpin is removed from both HDV ribozyme (the active structure) and SAM riboswitch (the SAM-bound structure) as Infernal does not handle pseudoknotted structure. In the active struc...

The electrochemical characteristics of an Au(111) electrode were investigated in 0.1 M KOH ethanol solutions containing various concentrations of decanethiol. Anodic and cathodic peaks corresponding to the oxidative adsorption and reductive desorption, respectively, of a self-assembled monolayer (SAM) of decanethiol were observed. Both peaks negatively shifted with the increase in the thiol con...

The free surface of water and the interface between water and a hydrophobic surface both have positive interface energies. The water density near a free surface drops below the bulk density, and thus it is expected that water near a hydrophobic surface will also show a density depletion. However, efforts by multiple groups to detect and characterize the predicted gap at water-hydrophobic interf...

DEVELOPMENT OF RUTHENIUM/TERPYRIDINE COMPLEXES FORWATER OXIDATIONbyDAKSHIKA C. WANNIARACHCHIMay 2014Advisor: Prof. Cláudio VeraniMajor: Chemistry (Physical)Degree: Doctor of PhilosophyThe work presented in the dissertation is focused on developing catalysts forwater oxidation. In this regard, a series of unsysmmetrical ruthenium complexes of type[Ru(t...

This report describes the use of surface plasmon spectroscopy to study the effect of surface wettability on the nonspecific adsorption of proteins and detergents to self-assembled monolayers (SAMs) of alkanethiolates on gold. The adsorption of both proteins and detergents to uncharged SAMs showed a general dependence on the wettability of the surface as determined by the contact angle of water ...

Electron tunneling is investigated for the alkanethiol self-assembled monolayers (SAMs) formed using three different device structures spanning from the nanometer to the micrometer scale. The measured current–voltage characteristics for the alkanethiol SAMs can be explained by the classical metal–insulator–metal tunneling model and the tunneling current exhibits overall exponential trend on the...

Arrays of Ta nanorods were grown by glancing angle deposition GLAD onto honeycomb Cr nanodot patterns that were evaporated onto Si substrates through a self-assembled monolayer of SiO2 nanospheres. Statistical size analyses from arrays of rods with variable average length l and width w, with 210 nm l 650 nm and 109 nm w 304 nm, show that the distribution in w broadens with increasing l and decr...