History matching is the process of updating a petroleum reservoir model using production data. It is a required step before a reservoir model is accepted for forecasting production. The process is normally carried out by flow simulation, which is very time-consuming. As a result, only a small number of simulation runs are conducted and the history matching results are normally unsatisfactory. I...

Developing an appropriate fix for a software bug often requires a detailed examination of the code as well as generation of appropriate test cases. However, certain categories of bugs are usually easy to fix. In this paper we focus on bugs that can be corrected with a one-line code change. As it turns out, one-line source code changes very often represent bug fixes. Moreover, a significant frac...

Background: Substance abuse is a social, and health problem in Middle Eastern countries such as Iran. One of its most devastating effects is domestic violence against children. This study examined the association between the history of parental substance abuse, and rate of child abuse in Ahvaz, Iran. Methods: This was a case-control study. The study population included all parents with high sch...

We propose a smooth formulation of multiple-point statistics that enables us to solve inverse problems using gradient-based optimization techniques. We introduce a differentiable function that quantifies the mismatch between multiple-point statistics of a training image and of a given model. We show that, by minimizing this function, any continuous image can be gradually transformed into an ima...

Computer architects and designers rely heavily on simulation. The downside of simulation is that it is very time-consuming — simulating an industry-standard benchmark on today’s fastest machines and simulators takes several weeks. A practical solution to the simulation problem is sampling. Sampled simulation selects a number of sampling units out of a complete program execution and only simulat...

Understanding the evolution of the Universe from the Big Bang to the current day is the fundamental goal of cosmology. A major part of this is the problem of structure formation: understanding the formation, growth and subsequent evolution of galaxies in the presence of Dark Matter. The world leading Galform group, based at the Institute of Computational Cosmology, Durham University, has develo...

the most important factor in donor-recipient matching for hematopoietic stem cell transplantation is their hla typing. for many patients, we can not find a full-matched donor. in high risk patients, one locus  mismatched related donors are suitable alternatives. (1, 2) since the matching of patients and their siblings usually is based on low resolution hla typing, the matching of one locus mism...

1 Institute for Computational Engineering and Sciences, The University of Texas at Austin, Austin, TX 78712, USA 2 Chevron ETC, San Ramon, CA 94583, USA 3 ConocoPhillips, Houston, TX 77252, USA 4 Institute for Computational Engineering and Sciences, Department of Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, Austin, TX 78712, USA 5 Department of Petroleum a...

History matching large reservoir models under a realistic geological continuity constraint remains an outstanding problem. We propose a new combined geostatistical and streamline-based method potentially capable of history matching large reservoir models, while accounting consistently for geological continuity as provided by a permeability histogram and variogram, and production data. While mos...