The present article examines whether derivational morphology shows evidence of an associative memory structure. A distributional analysis of stems of attested derivational forms revealed evidence of clustering around phonological properties (gangs) for all nonneutral affixes but only a few neutral affixes. Subjects' acceptability ratings for novel complex words revealed sensitivity to the gang ...

Protein kinase C (PKC) is activated by lipid second messengers or redox action, raising the question whether these activation modes involve the same or alternate mechanisms. Here we show that both lipid activators and oxidation target the zinc-finger domains of PKC, suggesting a unifying activation mechanism. We found that lipid agonist-binding or redox action leads to zinc release and disassem...

Synapses throughout the brain are modified through associative mechanisms in which one input provides an instructive signal for changes in the strength of a second coactivated input. In cerebellar Purkinje cells, climbing fiber synapses provide an instructive signal for plasticity at parallel fiber synapses. Here, we show that noradrenaline activates alpha2-adrenergic receptors to control short...

Stress and episodic memory impairment have previously been associated. Acute stress disorder (ASD) is a maladaptive stress response, which develops in some individuals following traumatic life events. Recently, the authors demonstrated a specific deficit in associative memory for emotionally neutral stimuli in ASD and posttraumatic stress disorder (PTSD). This study further tested the relations...

Long-term depression (LTD) is a form of synaptic plasticity that can be induced either by low-frequency stimulation of presynaptic fibers or in an associative manner by asynchronous pairing of presynaptic and postsynaptic activity. We investigated the induction mechanisms of associative LTD in CA1 pyramidal neurons of the hippocampus using whole-cell patch-clamp recordings and Ca(2+) imaging in...

Intercalation chemistry has dominated electrochemical energy storage for decades, and capacity worldwide now reached the terawatt-hour level. State-of-the-art intercalation cathodes Li-ion batteries operate within limits of transition metal cation electrochemistry, but discovery anion-redox processes in recent decades suggests rich opportunities substantially increasing stored densities. The di...