tuberculosis is one of the oldest diseases that affects humans. the cause of this disease is mycobacterium tuberculosis. this disease affects approximately 8.8 million people worldwide and led to over 3 million deaths in 1995. 95% of those affected and 98% of deaths occurred in developing countries. hepatic reactions constitute a major proportion of drug reactions to antituberculosis drugs bein...

objective(s): silver nanoparticles (ag-nps) are one of the most widely used nanomaterials recently. despite the wide application of nanomaterials, there is limited information concerning their impact on human health and the environment. this study aimed to find the effects of ag-nps (40 nm) on blood serum, liver and kidney tissues of homing pigeons (columbia livia).materials and methods: columb...

in the present study, changes of values of serum 17ß-estradiol (e2), asparate amino teransferase (ast), alanine amino transferase (alt) and lactate dehydrogenase (ldh) following intraperitoneal (i.p) injection with the aromatase inhibitor (ai) letrozole were investigated in rainbow trout (oncorhynchus mykiss). forty- eight apparently healthy rainbow trout (mean weight of 845 g) divided in four ...

The effect of aqueous leaf extract of Azadirachta indica (A. indica) was evaluated in paracetamol induced hepatotoxicity in rats. Liver necrosis was produced by administering single dose of paracetamol (2 g/kg, p.o.). The liver damage was evidenced by elevated levels of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma glutamyl transpeptidase (gamma-GT) and by histop...

The present study examined the impact of Lufenuron on biochemical parameters of albino mice.The biochemical parameters such as Alanine aminotransferase (ALT), Aspartate aminotransferase (AST) and Alkaline phosphatase (ALP) and Total protein in serum were observed. The mice exposed with Lufenuron 0.1520 mg/kg) for 30 days. The present study suggests that the level of AST, ALT and ALP were increa...

The levels of aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) in serum can help people diagnose body tissues especially the heart and the liver are injured or not. This article provides a comprehensive review of research activities that concentrate on AST/GOT and ALT/GPT detection techniques due to their clinical importance. The detection techniques include colorimet...

BACKGROUND AND PURPOSE The evaluation of adenosine deaminase (ADA) activity in sera of patients with hepatitis should be considered a useful tool in the monitoring of their clinical status. In this study, we aimed to determine the relationship between viral load, transaminase levels, and serum ADA levels in hepatitis B virus (HBV)- and hepatitis C virus (HCV)-infected patients. METHODS Sevent...

The present study was aimed to investigate the impact of Chromium trioxide on biochemical parameters of freshwater fish, Channa punctatus exposed to sub lethal concentration for 7, 15, 30 and 60 days. Aspartate transaminase (AST), Alanine transaminase (ALT), Orthophosphoric Monoester Phospho-hydrolase (OMP) and Orthophosphoric acid Monoester Phospho-hydrolase (OAMP) activities have been analyse...

The influence of anaemia on alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP) activities in dogs infected with B. canis was investigated. Samples of blood and serum from 230 infected dogs were divided into two groups: A (with anaemia) and B (without anaemia). The differences in the activities of the enzymes between both groups were not statisticall...

Case Summary: A 33-year old female with a history of Crohn’s disease presented with complaints of upper abdominal pain and bilious vomiting. She had been receiving Adalimumab and Mesalamine for treatment of Crohn’s disease. A liver panel revealed alkaline phosphatase (ALP): 188 IU/L, aspartate aminotransferase (AST): 1,638 IU/L, alanine transaminase (ALT): 592 IU/L, total bilirubin: 2.5 mg/dL, ...